Annotation of rs1800497

Allele A is not associated with response to lithium in people with Bipolar Disorder as compared to allele G.

This is from a review article which does not give all the details. It says that no association was found between the SNP and lithium response, but it does not state exactly how the alleles were compared.

From Publication

Pharmacogenetics of lithium response in bipolar disorder. Pharmacogenomics. 2010. McCarthy Michael J et al.
PMID:21047205(opens in new window) DOI:10.2217/pgs.10.127(opens in new window)

Gene

ANKK1

Variant

rs1800497

Phenotype Category

Efficacy

Association Significance

The study does not report on the significance of this association

PharmGKB ID

699639221

Score
More info on scoring

-1.5

Evidence for Clinical Annotations

This annotation has been used as evidence for the following clinical annotations.

    Study Parameters

    Study type

    Study size

    155

    Biogeographical group
    More info on groups

    European

    Note: Alleles in PharmGKB are mapped to the positive chromosomal strand. Therefore, variants in genes on the "minus" strand (eg. VKORC1) are complemented in PharmGKB annotations.

    History

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