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PharmGKB grants use of its contents for research purposes. The use of this data and knowledge is NOT available for redistribution. The PharmGKB is a NIH NIGMS sponsored research project (GM61374) funded to collect, encode, and disseminate knowledge about the impact of human genetic variations on drug response. The knowledge and data covered by this agreement include and are not limited to research variant annotations from the literature, clinical interpretations of these variants, gene summaries for very important pharmacogenes (VIPs), pathway and network diagrams, relationships between gene, drugs and diseases and all software that support the PharmGKB. This content is freely available to researchers in academia and industry for RESEARCH PURPOSES. Absent the issuance of a license by Stanford, the content shall not be used in any non-research commercial application in any form. If you are interested in using any contents from the PharmGKB for a product or with a plan to redistribute (e.g., a website), then you must obtain a separate license. Please contact Dr. Teri Klein if you require further information.
The PharmGKB is for research purposes. Prior to initiating research with this data as the researcher, you are obligated to know the requirements of HIPAA policy and be aware of other applicable privacy laws. Because this database may fall under HIPAA regulations, we must track all access to and use of the database. Specifically, we must and are able to determine what pieces of data you are accessing, how many times you access any particular pieces of data and the unique IP address of your computer. Each time you sign into the PharmGKB website, it will be assumed and documented that you have seen the entire contents of the database on that particular day and time. We are required to keep these records for institutional and federal auditing purposes. These requirements cannot be waived.
By accessing the data on the website, you are agreeing to the following:
If you do not agree, you will only have access to the general information pages.
This data is provided "as is", "where is" and without any express or implied warranties, including, but not limited to, any implied warranties of merchantability and/or fitness for a particular purpose. In no event shall Stanford University, nor its agents, employers or representatives be liable for any direct, indirect, incidental, special, exemplary, or consequential damages (including, but not limited to, procurement of substitute goods or services; loss of use, data, or profits; or business interruption) however caused and on any theory of liability, whether in contract, strict liability, or tort (including negligence or otherwise) arising in any way or form out of the use of this data, even if advised of the possibility of such damage.
All users assume the risk and responsibility for the accuracy, completeness or usefulness, or lack thereof, of any information, apparatus, product or process disclosed or that the use hereof would or would not infringe the rights of any other party.
Computer security at Stanford University is of utmost importance and maintenance of security is paramount. PharmGKB users are a large and diverse group with networks providing access to and from other computer systems located throughout the country. Today's high-speed computer networks provide users convenient, and often untraceable, access to our machines. For this, and other reasons, PharmGKB has adopted the policy that PharmGKB users may not share their accounts with any other individual at any time.
Your account is your personal responsibility. In the event of any incident or damage to our system in connection with your use, or the use by another, of your account, whether with or without your consent, you will be held liable for all damages, in any form, to our system, and for any related damages. Under no circumstances may a password be shared or disclosed to any third party besides the authorized user. In the event a password is shared with or disclosed to a third party, you will be held responsible for any damages the third party takes or causes due to actions related to the unauthorized use of your password. In the event of any litigation with regard to the foregoing, Stanford shall have the right to recovery of its attorneys' fees and costs from you.
Any user found sharing their account with another individual will have their account immediately deactivated. Any user found maliciously damaging or destroying another user's data or system programs, or using their account to illegally access another computer system will be referred to the State of California for prosecution of violations of Section 502 of the California Penal Code. A violation of Section 502 of the California Penal Code subjects you to both criminal, monetary penalties and possible imprisonment. Further, violation of Section 502(e) may subject you to civil punitive damages. In the event of such a violation, Stanford University will seek all remedies against you as provided by law.
If you would like to reproduce a PharmGKB pathway diagram, please acknowledge the copyright to PharmGKB and state that permission has been given by PharmGKB and Stanford University. In addition, please check the pathway diagram page to find out whether the pathway has been published in the Pharmacogenetics and Genomics journal. If there is such a citation on the pathway page, please use that. If not, please use the PharmGKB citation below.
Also, please send a brief email to firstname.lastname@example.org to inform us of which pathway diagram you are using and for what purpose.
M. Whirl-Carrillo, E.M. McDonagh, J. M. Hebert, L. Gong, K. Sangkuhl, C.F. Thorn, R.B. Altman and T.E. Klein. "Pharmacogenomics Knowledge for Personalized Medicine" Clinical Pharmacology & Therapeutics (2012) 92(4): 414-417.