Annotation of rs255100
Allele A is not associated with decreased response to salbutamol in people with Asthma as compared to allele T.
in replication cohort with adult patients.
From Publication
Association of corticotropin-releasing hormone receptor-2 genetic variants with acute bronchodilator response in asthma. Pharmacogenetics and genomics. 2008. Poon Audrey H et al.
Gene
Variant
Phenotype Category
Association Significance
PharmGKB ID
Score More info on scoring
Evidence for Clinical Annotations
This annotation has been used as evidence for the following clinical annotations.
Study Parameters
Study type
Study size
Association p-value
Biogeographical group More info on groups
Population description
Study Cohort: SEPRACOR (asthma patients enrolled in an adult study of ß2 – agonist conducted by Sepracor Inc.)
Note: Alleles in PharmGKB are mapped to the positive chromosomal strand. Therefore, variants in genes on the "minus" strand (eg. VKORC1) are complemented in PharmGKB annotations.
History
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