Annotation of rs255100

Allele A is not associated with decreased response to salbutamol in people with Asthma as compared to allele T.

in replication cohort with adult patients.

Gene

CRHR2

Variant

rs255100

Phenotype Category

Efficacy

Association Significance

The study reports this association is not significant

PharmGKB ID

699639212

Evidence for Clinical Annotations

This annotation has been used as evidence for the following clinical annotations.

    Study Parameters

    Study type

    cohort, clinical trial

    Study size

    427

    Association p-value

    = 0.78

    Biogeographical group
    More info on groups

    European

    Population description

    Study Cohort: SEPRACOR (asthma patients enrolled in an adult study of ß2 – agonist conducted by Sepracor Inc.)

    Note: Alleles in PharmGKB are mapped to the positive chromosomal strand. Therefore, variants in genes on the "minus" strand (eg. VKORC1) are complemented in PharmGKB annotations.

    History

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