Annotation of rs2839669

Allele T is not associated with dose of methadone in people with Heroin Dependence as compared to allele C.

From Publication

GAD1 but not GAD2 polymorphisms are associated with heroin addiction phenotypes. Neuroscience letters. 2020. Shi Yuhui et al.
PMID:31866536(opens in new window) DOI:10.1016/j.neulet.2019.134704(opens in new window)

Gene

GAD2

Variant

rs2839669

Phenotype Category

Dosage

Association Significance

The study reports this association is not significant

PharmGKB ID

1451138080

Score
More info on scoring

-2

Evidence for Clinical Annotations

This annotation has not been used as evidence for any clinical annotations.

Study Parameters

Study type

cohort

Study size

602

Association p-value

= 0.205

Biogeographical group
More info on groups

East Asian

Population description

Study Cohort: Uncorrected p-value given

Note: Alleles in PharmGKB are mapped to the positive chromosomal strand. Therefore, variants in genes on the "minus" strand (eg. VKORC1) are complemented in PharmGKB annotations.

History

No history available.