Annotation of rs16918941
Allele A is not associated with response to naltrexone in people with Tobacco Use Disorder as compared to allele G.
No significant association between this variant and smoking quit rate when naltrexone was used as augmentation to nicotine patch therapy.
From Publication
Lack of Association between Opioid-Receptor Genotypes and Smoking Cessation Outcomes in a Randomized, Controlled Naltrexone Trial. Alcohol and alcoholism (Oxford, Oxfordshire). 2019. Roche Daniel J O et al.
Gene
Variant
Phenotype Category
Association Significance
PharmGKB ID
Score More info on scoring
Evidence for Clinical Annotations
This annotation has not been used as evidence for any clinical annotations.
Study Parameters
Study type
Study size
Association p-value
Allele frequency
Biogeographical group More info on groups
Population description
men; women
Note: Alleles in PharmGKB are mapped to the positive chromosomal strand. Therefore, variants in genes on the "minus" strand (eg. VKORC1) are complemented in PharmGKB annotations.
History
No history available.