Annotation of rs6746030
Allele A is not associated with response to botulinum toxin type a in women with Migraine NOS as compared to allele G.
No significant difference in allele frequency between responders and non-responders.
From Publication
CALCA and TRPV1 genes polymorphisms are related to a good outcome in female chronic migraine patients treated with OnabotulinumtoxinA. The journal of headache and pain. 2019. Moreno-Mayordomo R et al.
Gene
Variant
Phenotype Category
Association Significance
PharmGKB ID
Score More info on scoring
Evidence for Clinical Annotations
This annotation has not been used as evidence for any clinical annotations.
Study Parameters
Study type
Study size
Association p-value
Allele frequency
Biogeographical group More info on groups
Population description
women
Study Cohort: Cases = responders Controls = Non-responders
Note: Alleles in PharmGKB are mapped to the positive chromosomal strand. Therefore, variants in genes on the "minus" strand (eg. VKORC1) are complemented in PharmGKB annotations.
History
No history available.