Annotation of rs6746030

Allele A is not associated with response to botulinum toxin type a in women with Migraine NOS as compared to allele G.

No significant difference in allele frequency between responders and non-responders.

Gene

SCN9A

Variant

rs6746030

Phenotype Category

Efficacy

Association Significance

The study reports this association is not significant

PharmGKB ID

1451104887

Score
More info on scoring

-1.5

Evidence for Clinical Annotations

This annotation has not been used as evidence for any clinical annotations.

Study Parameters

Study type

cohort, prospective

Study size

156 (cases=120; controls=36)

Association p-value

= 0.603

Allele frequency

A: case=0.134, control=0.111

Biogeographical group
More info on groups

European

Population description

women

Study Cohort: Cases = responders Controls = Non-responders

Note: Alleles in PharmGKB are mapped to the positive chromosomal strand. Therefore, variants in genes on the "minus" strand (eg. VKORC1) are complemented in PharmGKB annotations.

History

No history available.