Annotation of rs3827020

Allele C is not associated with exposure to nicotine in men as compared to allele T.

No significant association between this allele and status as a smoker or non-smoker.

Gene

CHRNA4

Variant

rs3827020

Phenotype Category

Other

Association Significance

The study reports this association is not significant

PharmGKB ID

1450930694

Score
More info on scoring

-1

Evidence for Clinical Annotations

This annotation has not been used as evidence for any clinical annotations.

Study Parameters

Study type

case/control

Study size

5055 (cases=2616; controls=2439)

Association p-value

= 0.340

Statistical analysis

OR: 1

Allele frequency

C=0.46

Biogeographical group
More info on groups

East Asian

Population description

men

Study Cohort: Uncorrected p-value given.

Note: Alleles in PharmGKB are mapped to the positive chromosomal strand. Therefore, variants in genes on the "minus" strand (eg. VKORC1) are complemented in PharmGKB annotations.

History

No history available.