Annotation of rs28386840
Allele T is not associated with response to methylphenidate in children with Attention Deficit Disorder with Hyperactivity as compared to allele A.
Clinical Global Impression-Severity (CGI-S) scale and the Children’s Global Assessment Scale (CGAS).
From Publication
Pharmacogenetics of methylphenidate in childhood attention-deficit/hyperactivity disorder: long-term effects. Scientific reports. 2017. Gomez-Sanchez Clara I et al.
Gene
Variant
Phenotype Category
Association Significance
Specialty Population
PharmGKB ID
Score More info on scoring
Evidence for Clinical Annotations
This annotation has been used as evidence for the following clinical annotations.
Study Parameters
Study type
Study size
Biogeographical group More info on groups
Population description
children (pediatrics)
Note: Alleles in PharmGKB are mapped to the positive chromosomal strand. Therefore, variants in genes on the "minus" strand (eg. VKORC1) are complemented in PharmGKB annotations.
History
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