Annotation of rs28386840

Allele T is not associated with response to methylphenidate in children with Attention Deficit Disorder with Hyperactivity as compared to allele A.

Clinical Global Impression-Severity (CGI-S) scale and the Children’s Global Assessment Scale (CGAS).

Gene

SLC6A2

Variant

rs28386840

Phenotype Category

Efficacy

Association Significance

The study reports this association is not significant

PharmGKB ID

1450376573

Evidence for Clinical Annotations

This annotation has been used as evidence for the following clinical annotations.

    Study Parameters

    Study type

    cohort

    Study size

    208

    Biogeographical group
    More info on groups

    European

    Population description

    children (pediatrics)

    Note: Alleles in PharmGKB are mapped to the positive chromosomal strand. Therefore, variants in genes on the "minus" strand (eg. VKORC1) are complemented in PharmGKB annotations.

    History

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