Annotation of rs12456693

Allele T is associated with increased response to clopidogrel in people with Coronary Artery Disease as compared to allele C.

This variant is associated with increased H4 concentration.

Gene

SLC14A2

Variant

rs12456693

Phenotype Category

Efficacy

Association Significance

The study reports this association is significant

PharmGKB ID

1450123149

Evidence for Clinical Annotations

This annotation has been used as evidence for the following clinical annotations.

    Study Parameters

    Study type

    cohort, GWAS

    Study size

    115

    Association p-value

    = 6.83e-5

    Biogeographical group
    More info on groups

    East Asian

    Population description

    Study Cohort: Chinese patients with coronary heart disease

    Note: Alleles in PharmGKB are mapped to the positive chromosomal strand. Therefore, variants in genes on the "minus" strand (eg. VKORC1) are complemented in PharmGKB annotations.

    History

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