Annotation of rs9923231
Allele T is associated with decreased dose of warfarin in children as compared to allele C.
with an approximate decrease of daily dose of 0.66mg.
From Publication
Pharmacogenetics of warfarin in a paediatric population: time in therapeutic range, initial and stable dosing and adverse effects. The pharmacogenomics journal. 2014. Hawcutt D B et al.
Gene
Variant
Phenotype Category
Association Significance
Specialty Population
PharmGKB ID
Score More info on scoring
Evidence for Clinical Annotations
This annotation has been used as evidence for the following clinical annotations.
Study Parameters
Study type
Study size
Association p-value
Biogeographical group More info on groups
Population description
children (pediatrics)
Note: Alleles in PharmGKB are mapped to the positive chromosomal strand. Therefore, variants in genes on the "minus" strand (eg. VKORC1) are complemented in PharmGKB annotations.
History
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