Annotation of rs1799853

Allele T is associated with decreased metabolism of warfarin as compared to allele C.

Impaired metabolism was found for S-warfarin. T= CYP2C9*2; C= CYP2C9*1.

Gene

CYP2C9

Variant

rs1799853

Phenotype Category

Metabolism/PK

Association Significance

The study does not report on the significance of this association

PharmGKB ID

1183701883

Score
More info on scoring

0.125

Evidence for Clinical Annotations

Study Parameters

Study type

Population description

Study Cohort: enzymes were expressed in HepG cells

Note: Alleles in PharmGKB are mapped to the positive chromosomal strand. Therefore, variants in genes on the "minus" strand (eg. VKORC1) are complemented in PharmGKB annotations.

History

No history available.