Annotation of rs6877011

Genotypes CG + GG are not associated with response to cisplatin, fluorouracil and oxaliplatin in people with Stomach Neoplasms as compared to genotype CC.

No significant association was found in progression free survival or overall survival.

Gene

FLT4

Variant

rs6877011

Phenotype Category

Efficacy

Association Significance

The study reports this association is not significant

PharmGKB ID

1183701035

Score
More info on scoring

-1.25

Evidence for Clinical Annotations

This annotation has not been used as evidence for any clinical annotations.

Study Parameters

Study type

cohort

Study size

94

Association p-value

> 0.05

Population description

Study Cohort: Patients with HER-2 negative metastic gastric cancer recieving platinum-based chemotherapy (fluorouracil+cisplatin or fluorouracil+oxaliplatin).

Note: Alleles in PharmGKB are mapped to the positive chromosomal strand. Therefore, variants in genes on the "minus" strand (eg. VKORC1) are complemented in PharmGKB annotations.

History

No history available.