Annotation of rs17183814
Allele A is not associated with response to carbamazepine or valproic acid in people with Epilepsy as compared to allele G.
No significant association was found with this SNP and response to epilepsy drugs after 1000 permutation testing for each marker or haplotype and Bonferroni correction.
From Publication
Gene
Variant
Phenotype Category
Association Significance
PharmGKB ID
Score More info on scoring
Evidence for Clinical Annotations
This annotation has been used as evidence for the following clinical annotations.
Study Parameters
Study type
Study size
Association p-value
Allele frequency
Biogeographical group More info on groups
Population description
Study Cohort: Comparison of allele frequencies/ genotype frequencies in responders vs non-responders. Drug response defined as completely seizure-free for at least 1 year during monotherapy treatment. Drug resistance defined as a seizure occurring within 1 year period of treatment.
Note: Alleles in PharmGKB are mapped to the positive chromosomal strand. Therefore, variants in genes on the "minus" strand (eg. VKORC1) are complemented in PharmGKB annotations.