Irinotecan pathway genotype analysis to predict pharmacokinetics by Mathijssen Ron H J, Marsh Sharon, Karlsson Mats O, Xie Rujia, Baker Sharyn D, Verweij Jaap, Sparreboom Alex, McLeod Howard L in Clinical cancer research : an official journal of the American Association for Cancer Research (2003). PubMed


The purpose was to explore the relationships between irinotecan disposition and allelic variants of genes coding for adenosine triphosphate binding cassette transporters and enzymes of putative relevance for irinotecan.

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