PharmGKB Publications

Peer-reviewed scientific articles written or contributed by PharmGKB staff and other researchers. PharmGKB pathways and important pharmacogene summaries (VIPs) are published monthly in the journal Pharmacogenetics and Genomics.

Total Publications: 293

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Pathway Publications: 42

  1. PharmGKB summary: voriconazole pathway, pharmacokinetics. Pharmacogenetics and genomics. 2017. Barbarino Julia M, Owusu Obeng Aniwaa, Klein Teri E, Altman Russ B. PubMed
  2. PharmGKB summary: sorafenib pathways. Pharmacogenetics and genomics. 2017. Gong Li, Giacomini Marilyn M, Giacomini Craig, Maitland Michael L, Altman Russ B, Klein Teri E. PubMed
  3. PharmGKB summary: ivacaftor pathway, pharmacokinetics/pharmacodynamics. Pharmacogenetics and genomics. 2016. Fohner Alison E, McDonagh Ellen M, Clancy John P, Whirl Carrillo Michelle, Altman Russ B, Klein Teri E. PubMed
  4. PharmGKB summary: isoniazid pathway, pharmacokinetics. Pharmacogenetics and genomics. 2016. Klein Daniel J, Boukouvala Sotiria, McDonagh Ellen M, Shuldiner Scott R, Laurieri Nicola, Thorn Caroline F, Altman Russ B, Klein Teri E. PubMed
  5. PharmGKB summary: succinylcholine pathway, pharmacokinetics/pharmacodynamics. Pharmacogenetics and genomics. 2015. Alvarellos Maria L, McDonagh Ellen M, Patel Sephalie, McLeod Howard L, Altman Russ B, Klein Teri E. PubMed
  6. PharmGKB summary: pathways of acetaminophen metabolism at the therapeutic versus toxic doses. Pharmacogenetics and genomics. 2015. Mazaleuskaya Liudmila L, Sangkuhl Katrin, Thorn Caroline F, FitzGerald Garret A, Altman Russ B, Klein Teri E. PubMed
  7. PharmGKB summary: peginterferon-alpha pathway. Pharmacogenetics and genomics. 2015. Shuldiner Scott R, Gong Li, Muir Andrew J, Altman Russ B, Klein Teri E. PubMed
  8. PharmGKB summary: Efavirenz pathway, pharmacokinetics. Pharmacogenetics and genomics. 2015. McDonagh Ellen M, Lau Johnathan L, Alvarellos Maria L, Altman Russ B, Klein Teri E. PubMed
  9. PharmGKB summary: ibuprofen pathways. Pharmacogenetics and genomics. 2014. Mazaleuskaya Liudmila L, Theken Katherine N, Gong Li, Thorn Caroline F, FitzGerald Garret A, Altman Russ B, Klein Teri E. PubMed
  10. PharmGKB summary: gemcitabine pathway. Pharmacogenetics and genomics. 2014. Alvarellos Maria L, Lamba Jatinder, Sangkuhl Katrin, Thorn Caroline F, Wang Liewei, Klein Daniel J, Altman Russ B, Klein Teri E. PubMed
  11. PharmGKB summary: uric acid-lowering drugs pathway, pharmacodynamics. Pharmacogenetics and genomics. 2014. McDonagh Ellen M, Thorn Caroline F, Callaghan John T, Altman Russ B, Klein Teri E. PubMed
  12. PharmGKB summary: tramadol pathway. Pharmacogenetics and genomics. 2014. Gong Li, Stamer Ulrike M, Tzvetkov Mladen V, Altman Russ B, Klein Teri E. PubMed
  13. PharmGKB summary: abacavir pathway. Pharmacogenetics and genomics. 2014. Barbarino Julia M, Kroetz Deanna L, Altman Russ B, Klein Teri E. PubMed
  14. PharmGKB summary: ifosfamide pathways, pharmacokinetics and pharmacodynamics. Pharmacogenetics and genomics. 2014. Lowenberg Daniella, Thorn Caroline F, Desta Zeruesenay, Flockhart David A, Altman Russ B, Klein Teri E. PubMed
  15. PharmGKB summary: mycophenolic acid pathway. Pharmacogenetics and genomics. 2013. Lamba Vishal, Sangkuhl Katrin, Sanghavi Kinjal, Fish Alyssa, Altman Russ B, Klein Teri E. PubMed
  16. PharmGKB summary: venlafaxine pathway. Pharmacogenetics and genomics. 2013. Sangkuhl Katrin, Stingl Julia C, Turpeinen Miia, Altman Russ B, Klein Teri E. PubMed
  17. PharmGKB summary: methylene blue pathway. Pharmacogenetics and genomics. 2013. McDonagh Ellen M, Bautista José M, Youngster Ilan, Altman Russ B, Klein Teri E. PubMed
  18. PharmGKB summary: Diuretics pathway, pharmacodynamics. Pharmacogenetics and genomics. 2013. Thorn Caroline F, Ellison David H, Turner Stephen T, Altman Russ B, Klein Teri E. PubMed
  19. PharmGKB summary: cyclosporine and tacrolimus pathways. Pharmacogenetics and genomics. 2013. Barbarino Julia M, Staatz Christine E, Venkataramanan Raman, Klein Teri E, Altman Russ B. PubMed
  20. PharmGKB summary: tamoxifen pathway, pharmacokinetics. Pharmacogenetics and genomics. 2013. Klein Daniel J, Thorn Caroline F, Desta Zeruesenay, Flockhart David A, Altman Russ B, Klein Teri E. PubMed
  21. Valproic acid pathway: pharmacokinetics and pharmacodynamics. Pharmacogenetics and genomics. 2013. Ghodke-Puranik Yogita, Thorn Caroline F, Lamba Jatinder K, Leeder J Steven, Song Wen, Birnbaum Angela K, Altman Russ B, Klein Teri E. PubMed
  22. PharmGKB summary: zidovudine pathway. Pharmacogenetics and genomics. 2012. Ghodke Yogita, Anderson Peter L, Sangkuhl Katrin, Lamba Jatinder, Altman Russ B, Klein Teri E. PubMed
  23. Metformin pathways: pharmacokinetics and pharmacodynamics. Pharmacogenetics and genomics. 2012. Gong Li, Goswami Srijib, Giacomini Kathleen M, Altman Russ B, Klein Teri E. PubMed
  24. PharmGKB summary: phenytoin pathway. Pharmacogenetics and genomics. 2012. Thorn Caroline F, Whirl-Carrillo Michelle, Leeder J Steven, Klein Teri E, Altman Russ B. PubMed
  25. Celecoxib pathways: pharmacokinetics and pharmacodynamics. Pharmacogenetics and genomics. 2012. Gong Li, Thorn Caroline F, Bertagnolli Monica M, Grosser Tilo, Altman Russ B, Klein Teri E. PubMed
  26. PharmGKB summary: caffeine pathway. Pharmacogenetics and genomics. 2012. Thorn Caroline F, Aklillu Eleni, McDonagh Ellen M, Klein Teri E, Altman Russ B. PubMed
  27. PharmGKB summary: carbamazepine pathway. Pharmacogenetics and genomics. 2011. Thorn Caroline F, Leckband Susan G, Kelsoe John, Steven Leeder J, Müller Daniel J, Klein Teri E, Altman Russ B. PubMed
  28. PharmGKB summary: citalopram pharmacokinetics pathway. Pharmacogenetics and genomics. 2011. Sangkuhl Katrin, Klein Teri E, Altman Russ B. PubMed
  29. PharmGKB summary: methotrexate pathway. Pharmacogenetics and genomics. 2011. Mikkelsen Torben S, Thorn Caroline F, Yang Jun J, Ulrich Cornelia M, French Deborah, Zaza Gianluigi, Dunnenberger Henry M, Marsh Sharon, McLeod Howard L, Giacomini Kathy, Becker Mara L, Gaedigk Roger, Leeder James Steven, Kager Leo, Relling Mary V, Evans William, Klein Teri E, Altman Russ B. PubMed
  30. Bisphosphonates pathway. Pharmacogenetics and genomics. 2011. Gong Li, Altman Russ B, Klein Teri E. PubMed
  31. Doxorubicin pathways: pharmacodynamics and adverse effects. Pharmacogenetics and genomics. 2010. Thorn Caroline F, Oshiro Connie, Marsh Sharon, Hernandez-Boussard Tina, McLeod Howard, Klein Teri E, Altman Russ B. PubMed
  32. Platelet aggregation pathway. Pharmacogenetics and genomics. 2010. Sangkuhl Katrin, Shuldiner Alan R, Klein Teri E, Altman Russ B. PubMed
  33. Thiopurine pathway. Pharmacogenetics and genomics. 2010. Zaza Gianluigi, Cheok Meyling, Krynetskaia Natalia, Thorn Caroline, Stocco Gabriele, Hebert Joan M, McLeod Howard, Weinshilboum Richard M, Relling Mary V, Evans William E, Klein Teri E, Altman Russ B. PubMed
  34. Clopidogrel pathway. Pharmacogenetics and genomics. 2010. Sangkuhl Katrin, Klein Teri E, Altman Russ B. PubMed
  35. PharmGKB summary: fluoropyrimidine pathways. Pharmacogenetics and genomics. 2010. Thorn Caroline F, Marsh Sharon, Carrillo Michelle Whirl, McLeod Howard L, Klein Teri E, Altman Russ B. PubMed
  36. Vascular endothelial growth factor pathway. Pharmacogenetics and genomics. 2010. Maitland Michael L, Lou Xing Jian, Ramirez Jacqueline, Desai Apurva A, Berlin Dorit S, McLeod Howard L, Weichselbaum Ralph R, Ratain Mark J, Altman Russ B, Klein Teri E. PubMed
  37. Taxane Pathway. Pharmacogenetics and genomics. 2009. Oshiro Connie, Marsh Sharon, McLeod Howard, Carrillo Michelle, Klein Teri, Altman Russ. PubMed
  38. Selective serotonin reuptake inhibitors pathway. Pharmacogenetics and genomics. 2009. Sangkuhl Katrin, Klein Teri E, Altman Russ B. PubMed
  39. Antiestrogen pathway (aromatase inhibitor). Pharmacogenetics and genomics. 2009. Desta Zeruesenay, Nguyen Anne, Flockhart David, Skaar Todd, Fletcher Rebecca, Weinshilboum Richard, Berlin Dorit S, Klein Teri E, Altman Russ B. PubMed
  40. Codeine and morphine pathway. Pharmacogenetics and genomics. 2009. Thorn Caroline F, Klein Teri E, Altman Russ B. PubMed
  41. Etoposide pathway. Pharmacogenetics and genomics. 2009. Yang Jun, Bogni Alessia, Schuetz Erin G, Ratain Mark, Dolan M Eileen, McLeod Howard, Gong Li, Thorn Caroline, Relling Mary V, Klein Teri E, Altman Russ B. PubMed
  42. Platinum pathway. Pharmacogenetics and genomics. 2009. Marsh Sharon, McLeod Howard, Dolan Eileen, Shukla Sunita J, Rabik Cara A, Gong Li, Hernandez-Boussard Tina, Lou Xing Jian, Klein Teri E, Altman Russ B. PubMed

Guideline Publications: 27

  1. Clinical pharmacogenetics implementation consortium (cpic) guideline for pharmacogenetics-guided warfarin dosing: 2017 update. Clinical pharmacology and therapeutics. 2017. Johnson Julie A, Caudle Kelly E, Gong Li, Whirl-Carrillo Michelle, Stein C Michael, Scott Stuart A, Lee Ming Ta Michael, Gage Brian F, Kimmel Stephen E, Perera Minoli A, Anderson Jeffrey L, Pirmohamed Munir, Klein Teri E, Limdi Nita A, Cavallari Larisa H, Wadelius Mia. PubMed
  2. Clinical Pharmacogenetics Implementation Consortium (CPIC) Guideline for CYP2D6 Genotype and Use of Ondansetron and Tropisetron. Clinical pharmacology and therapeutics. 2016. Bell Gillian C, Caudle Kelly E, Whirl-Carrillo Michelle, Gordon Ronald J, Hikino Keiko, Prows Cynthia A, Gaedigk Andrea, Agundez Jose A G, Sadhasivam Senthilkumar, Klein Teri E, Schwab Matthias. PubMed
  3. Clinical Pharmacogenetics Implementation Consortium (CPIC®) Guideline for CYP2C19 and Voriconazole Therapy. Clinical pharmacology and therapeutics. 2016. Moriyama Brad, Obeng Aniwaa Owusu, Barbarino Julia, Penzak Scott R, Henning Stacey A, Scott Stuart A, Agúndez José A G, Wingard John R, McLeod Howard L, Klein Teri E, Cross Shane, Caudle Kelly E, Walsh Thomas J. PubMed
  4. Clinical Pharmacogenetics Implementation Consortium Guideline (CPIC®) for CYP2D6 and CYP2C19 Genotypes and Dosing of Tricyclic Antidepressants: 2016 Update. Clinical pharmacology and therapeutics. 2016. Kevin Hicks J, Sangkuhl Katrin, Swen Jesse J, Ellingrod Vicki L, Müller Daniel J, Shimoda Kazutaka, Bishop Jeffrey R, Kharasch Evan D, Skaar Todd C, Gaedigk Andrea, Dunnenberger Henry M, Klein Teri E, Caudle Kelly E, Stingl Julia C. PubMed
  5. Clinical Pharmacogenetics Implementation Consortium (CPIC) Guideline for UGT1A1 and Atazanavir Prescribing. Clinical pharmacology and therapeutics. 2015. Gammal Roseann S, Court Michael H, Haidar Cyrine E, Iwuchukwu Otito Frances, Gaur Aditya H, Alvarellos Maria, Guillemette Chantal, Lennox Jeffrey L, Whirl-Carrillo Michelle, Brummel Sean, Ratain Mark J, Klein Teri E, Schackman Bruce R, Caudle Kelly E, Haas David W. PubMed
  6. Clinical Pharmacogenetics Implementation Consortium (CPIC) guidelines for human leukocyte antigen B (HLA-B) genotype and allopurinol dosing: 2015 update. Clinical pharmacology and therapeutics. 2015. Saito Y, Stamp L K, Caudle K E, Hershfield M S, McDonagh E M, Callaghan J T, Tassaneeyakul W, Mushiroda T, Kamatani N, Goldspiel B R, Phillips E J, Klein T E, Lee Mtm. PubMed
  7. Clinical Pharmacogenetics Implementation Consortium (CPIC) Guideline for CYP2D6 and CYP2C19 Genotypes and Dosing of Selective Serotonin Reuptake Inhibitors. Clinical pharmacology and therapeutics. 2015. Hicks J Kevin, Bishop Jeffrey R, Sangkuhl Katrin, Müller Daniel J, Ji Yuan, Leckband Susan G, Leeder J Steven, Graham Rebecca L, Chiulli Dana L, LLerena Adrián, Skaar Todd C, Scott Stuart A, Stingl Julia C, Klein Teri E, Caudle Kelly E, Gaedigk Andrea. PubMed
  8. Clinical pharmacogenetics implementation consortium (CPIC) guidelines for CYP3A5 genotype and tacrolimus dosing. Clinical pharmacology and therapeutics. 2015. Birdwell Kelly A, Decker Brian, Barbarino Julia M, Peterson Josh F, Stein C Michael, Sadee Wolfgang, Wang Danxin, Vinks Alexander A, He Yijing, Swen Jesse J, Leeder J Steven, van Schaik R H N, Thummel Kenneth E, Klein Teri E, Caudle Kelly E, MacPhee Iain A M. PubMed
  9. Clinical Pharmacogenetics Implementation Consortium (CPIC) Guidelines for CYP2C9 and HLA-B Genotype and Phenytoin Dosing. Clinical pharmacology and therapeutics. 2014. Caudle Kelly E, Rettie Allan E, Whirl-Carrillo Michelle, Smith Lisa H, Mintzer Scott E, Lee Ming Ta Michael, Klein Teri E, Callaghan J Thomas. PubMed
  10. The Clinical Pharmacogenetics Implementation Consortium (CPIC) guideline for SLCO1B1 and simvastatin-induced myopathy: 2014 update. Clinical pharmacology and therapeutics. 2014. Ramsey Laura B, Johnson Samuel G, Caudle Kelly E, Haidar Cyrine E, Voora Deepak, Wilke Russell A, Maxwell Whitney D, McLeod Howard L, Krauss Ronald M, Roden Dan M, Feng Qiping, Cooper-DeHoff Rhonda M, Gong Li, Klein Teri E, Wadelius Mia, Niemi Mikko. PubMed
  11. Clinical Pharmacogenetics Implementation Consortium (CPIC) Guidelines for Rasburicase Therapy in the context of G6PD Deficiency Genotype. Clinical pharmacology and therapeutics. 2014. Relling Mary V, McDonagh Ellen M, Chang Tamara, Caudle Kelly E, McLeod Howard L, Haidar Cyrine E, Klein Teri, Luzzatto Lucio. PubMed
  12. Clinical Pharmacogenetics Implementation Consortium (CPIC) Guidelines for Ivacaftor Therapy in the Context of CFTR Genotype. Clinical pharmacology and therapeutics. 2014. Clancy John P, Johnson Samuel G, Yee Sook Wah, McDonagh Ellen M, Caudle Kelly E, Klein Teri E, Cannavo Matthew, Giacomini Kathleen M. PubMed
  13. Clinical Pharmacogenetics Implementation Consortium (CPIC) Guidelines for HLA-B Genotype and Abacavir Dosing: 2014 update. Clinical pharmacology and therapeutics. 2014. Martin Michael A, Hoffman James M, Freimuth Robert R, Klein Teri E, Dong Betty J, Pirmohamed Munir, Hicks J Kevin, Wilkinson Mark R, Haas David W, Kroetz Deanna L. PubMed
  14. Clinical Pharmacogenetics Implementation Consortium (CPIC) guidelines for cytochrome P450 2D6 (CYP2D6) genotype and codeine therapy: 2014 Update. Clinical pharmacology and therapeutics. 2014. Crews Kristine R, Gaedigk Andrea, Dunnenberger Henry M, Leeder J Steve, Klein Teri E, Caudle Kelly E, Haidar Cyrine E, Shen Danny D, Callaghan John T, Sadhasivam Senthilkumar, Prows Cynthia A, Kharasch Evan D, Skaar Todd C. PubMed
  15. Clinical Pharmacogenetics Implementation Consortium (CPIC) guidelines for IFNL3 (IL28B) genotype and peginterferon alpha based regimens. Clinical pharmacology and therapeutics. 2013. Muir Andrew J, Gong Li, Johnson Samuel G, Michael Lee Ming Ta, Williams Marc S, Klein Teri E, Caudle Kelly E, Nelson David R. PubMed
  16. Clinical Pharmacogenetics Implementation Consortium Guidelines for Dihydropyrimidine Dehydrogenase Genotype and Fluoropyrimidine Dosing. Clinical pharmacology and therapeutics. 2013. Caudle Kelly E, Thorn Caroline F, Klein Teri E, Swen Jesse J, McLeod Howard L, Diasio Robert B, Schwab Matthias. PubMed
  17. Clinical Pharmacogenetics Implementation Consortium (CPIC) Guidelines for HLA-B Genotype and Carbamazepine Dosing. Clinical pharmacology and therapeutics. 2013. Leckband Susan G, Kelsoe John R, Dunnenberger H Mark, George Alfred L, Tran Eric, Berger Reisel, Müller Daniel J, Whirl-Carrillo Michelle, Caudle Kelly E, Pirmohamed Munir. PubMed
  18. Clinical Pharmacogenetics Implementation Consortium (CPIC) guidelines for cytochrome P450-2C19 (CYP2C19) genotype and clopidogrel therapy: 2013 Update. Clinical pharmacology and therapeutics. 2013. Scott Stuart A, Sangkuhl Katrin, Stein C Michael, Hulot Jean-Sébastien, Mega Jessica L, Roden Dan M, Klein Teri E, Sabatine Marc S, Johnson Julie A, Shuldiner Alan R. PubMed
  19. Clinical Pharmacogenetics Implementation Consortium Guideline for CYP2D6 and CYP2C19 Genotypes and Dosing of Tricyclic Antidepressants. Clinical pharmacology and therapeutics. 2013. Hicks J K, Swen J J, Thorn C F, Sangkuhl K, Kharasch E D, Ellingrod V L, Skaar T C, Müller D J, Gaedigk A, Stingl J C. PubMed
  20. Clinical Pharmacogenetics Implementation Consortium Guidelines for Thiopurine Methyltransferase Genotype and Thiopurine Dosing: 2013 Update. Clinical pharmacology and therapeutics. 2013. Relling M V, Gardner E E, Sandborn W J, Schmiegelow K, Pui C-H, Yee S W, Stein C M, Carrillo M, Evans W E, Hicks J K, Schwab M, Klein T E. PubMed
  21. Clinical Pharmacogenetics Implementation Consortium Guidelines for Human Leukocyte Antigen-B Genotype and Allopurinol Dosing. Clinical pharmacology and therapeutics. 2012. Hershfield M S, Callaghan J T, Tassaneeyakul W, Mushiroda T, Thorn C F, Klein T E, Lee M T M. PubMed
  22. The Clinical Pharmacogenomics Implementation Consortium: CPIC Guideline for SLCO1B1 and Simvastatin-Induced Myopathy. Clinical pharmacology and therapeutics. 2012. Wilke R A, Ramsey L B, Johnson S G, Maxwell W D, McLeod H L, Voora D, Krauss R M, Roden D M, Feng Q, Cooper-Dehoff R M, Gong L, Klein T E, Wadelius M, Niemi M. PubMed
  23. Clinical Pharmacogenetics Implementation Consortium Guidelines for HLA-B Genotype and Abacavir Dosing. Clinical pharmacology and therapeutics. 2012. Martin M A, Klein T E, Dong B J, Pirmohamed M, Haas D W, Kroetz D L. PubMed
  24. Clinical Pharmacogenetics Implementation Consortium (CPIC) Guidelines for Codeine Therapy in the Context of Cytochrome P450 2D6 (CYP2D6) Genotype. Clinical pharmacology and therapeutics. 2011. Crews K R, Gaedigk A, Dunnenberger H M, Klein T E, Shen D D, Callaghan J T, Kharasch E D, Skaar T C. PubMed
  25. Clinical Pharmacogenetics Implementation Consortium Guidelines for CYP2C9 and VKORC1 Genotypes and Warfarin Dosing. Clinical pharmacology and therapeutics. 2011. Johnson J A, Gong L, Whirl-Carrillo M, Gage B F, Scott S A, Stein C M, Anderson J L, Kimmel S E, Lee M T M, Pirmohamed M, Wadelius M, Klein T E, Altman R B. PubMed
  26. Clinical Pharmacogenetics Implementation Consortium Guidelines for Cytochrome P450-2C19 (CYP2C19) Genotype and Clopidogrel Therapy. Clinical pharmacology and therapeutics. 2011. Scott S A, Sangkuhl K, Gardner E E, Stein C M, Hulot J-S, Johnson J A, Roden D M, Klein T E, Shuldiner A R. PubMed
  27. Clinical pharmacogenetics implementation consortium guidelines for thiopurine methyltransferase genotype and thiopurine dosing. Clinical pharmacology and therapeutics. 2011. Relling M V, Gardner E E, Sandborn W J, Schmiegelow K, Pui C-H, Yee S W, Stein C M, Carrillo M, Evans W E, Klein T E. PubMed

VIP Publications: 33

  1. PharmGKB summary: very important pharmacogene information for MT-RNR1. Pharmacogenetics and genomics. 2016. Barbarino Julia M, McGregor Tracy L, Altman Russ B, Klein Teri E. PubMed
  2. PharmGKB Summary: very important pharmacogene information for RYR1. Pharmacogenetics and genomics. 2015. Alvarellos Maria L, Krauss Ronald M, Wilke Russell A, Altman Russ B, Klein Teri E. PubMed
  3. PharmGKB summary: very important pharmacogene information for human leukocyte antigen B. Pharmacogenetics and genomics. 2015. Barbarino Julia M, Kroetz Deanna L, Klein Teri E, Altman Russ B. PubMed
  4. PharmGKB summary: very important pharmacogene information for CFTR. Pharmacogenetics and genomics. 2014. McDonagh Ellen M, Clancy John P, Altman Russ B, Klein Teri E. PubMed
  5. PharmGKB summary: very important pharmacogene information for CYP4F2. Pharmacogenetics and genomics. 2014. Alvarellos Maria L, Sangkuhl Katrin, Daneshjou Roxana, Whirl-Carrillo Michelle, Altman Russ B, Klein Teri E. PubMed
  6. PharmGKB summary: very important pharmacogene information for N-acetyltransferase 2. Pharmacogenetics and genomics. 2014. McDonagh Ellen M, Boukouvala Sotiria, Aklillu Eleni, Hein David W, Altman Russ B, Klein Teri E. PubMed
  7. PharmGKB summary: very important pharmacogene information for SLC22A1. Pharmacogenetics and genomics. 2014. Goswami Srijib, Gong Li, Giacomini Kathleen, Altman Russ B, Klein Teri E. PubMed
  8. PharmGKB summary: very important pharmacogene information for UGT1A1. Pharmacogenetics and genomics. 2014. Barbarino Julia M, Haidar Cyrine E, Klein Teri E, Altman Russ B. PubMed
  9. PharmGKB summary: very important pharmacogene information for cytochrome P450, family 2, subfamily C, polypeptide 8. Pharmacogenetics and genomics. 2013. Aquilante Christina L, Niemi Mikko, Gong Li, Altman Russ B, Klein Teri E. PubMed
  10. PharmGKB summary: very important pharmacogene information for the epidermal growth factor receptor. Pharmacogenetics and genomics. 2013. Hodoglugil Ugur, Carrillo Michelle W, Hebert Joan M, Karachaliou Niki, Rosell Rafael C, Altman Russ B, Klein Teri E. PubMed
  11. PharmGKB summary: very important pharmacogene information for GSTT1. Pharmacogenetics and genomics. 2012. Thorn Caroline F, Ji Yuan, Weinshilboum Richard M, Altman Russ B, Klein Teri E. PubMed
  12. PharmGKB summary: very important pharmacogene information for CYP3A5. Pharmacogenetics and genomics. 2012. Lamba Jatinder, Hebert Joan M, Schuetz Erin G, Klein Teri E, Altman Russ B. PubMed
  13. Very important pharmacogene summary for VDR. Pharmacogenetics and genomics. 2012. Poon Audrey H, Gong Li, Brasch-Andersen Charlotte, Litonjua Augusto A, Raby Benjamin A, Hamid Qutayba, Laprise Catherine, Weiss Scott T, Altman Russ B, Klein Teri E. PubMed
  14. PharmGKB summary: very important pharmacogene information for cytochrome P-450, family 2, subfamily A, polypeptide 6. Pharmacogenetics and genomics. 2012. McDonagh Ellen M, Wassenaar Catherine, David Sean P, Tyndale Rachel F, Altman Russ B, Whirl-Carrillo Michelle, Klein Teri E. PubMed
  15. PharmGKB summary: very important pharmacogene information for G6PD. Pharmacogenetics and genomics. 2012. McDonagh Ellen M, Thorn Caroline F, Bautista José M, Youngster Ilan, Altman Russ B, Klein Teri E. PubMed
  16. PharmGKB summary: very important pharmacogene information for CYP1A2. Pharmacogenetics and genomics. 2011. Thorn Caroline F, Aklillu Eleni, Klein Teri E, Altman Russ B. PubMed
  17. PharmGKB summary: very important pharmacogene information for cytochrome P450, family 2, subfamily C, polypeptide 19. Pharmacogenetics and genomics. 2011. Scott Stuart A, Sangkuhl Katrin, Shuldiner Alan R, Hulot Jean-Sébastien, Thorn Caroline F, Altman Russ B, Klein Teri E. PubMed
  18. Very important pharmacogene summary: ABCB1 (MDR1, P-glycoprotein). Pharmacogenetics and genomics. 2011. Hodges Laura M, Markova Svetlana M, Chinn Leslie W, Gow Jason M, Kroetz Deanna L, Klein Teri E, Altman Russ B. PubMed
  19. PharmGKB: very important pharmacogene--HMGCR. Pharmacogenetics and genomics. 2011. Medina Marisa Wong, Sangkuhl Katrin, Klein Teri E, Altman Russ B. PubMed
  20. KCNH2 pharmacogenomics summary. Pharmacogenetics and genomics. 2010. Oshiro Connie, Thorn Caroline F, Roden Dan M, Klein Teri E, Altman Russ B. PubMed
  21. PharmGKB summary: very important pharmacogene information for PTGS2. Pharmacogenetics and genomics. 2010. Thorn Caroline F, Grosser Tilo, Klein Teri E, Altman Russ B. PubMed
  22. SLC19A1 pharmacogenomics summary. Pharmacogenetics and genomics. 2010. Yee Sook Wah, Gong Li, Badagnani Ilaria, Giacomini Kathleen M, Klein Teri E, Altman Russ B. PubMed
  23. VKORC1 pharmacogenomics summary. Pharmacogenetics and genomics. 2010. Owen Ryan P, Gong Li, Sagreiya Hersh, Klein Teri E, Altman Russ B. PubMed
  24. PharmGKB summary: cytochrome P450, family 2, subfamily J, polypeptide 2: CYP2J2. Pharmacogenetics and genomics. 2010. Berlin Dorit S, Sangkuhl Katrin, Klein Teri E, Altman Russ B. PubMed
  25. PharmGKB summary: dopamine receptor D2. Pharmacogenetics and genomics. 2010. Mi Huaiyu, Thomas Paul D, Ring Huijun Z, Jiang Ruhong, Sangkuhl Katrin, Klein Teri E, Altman Russ B. PubMed
  26. PharmGKB summary: very important pharmacogene information for CYP2B6. Pharmacogenetics and genomics. 2010. Thorn Caroline F, Lamba Jatinder K, Lamba Vishal, Klein Teri E, Altman Russ B. PubMed
  27. Very important pharmacogene summary: thiopurine S-methyltransferase. Pharmacogenetics and genomics. 2010. Wang Liewei, Pelleymounter Linda, Weinshilboum Richard, Johnson Julie A, Hebert Joan M, Altman Russ B, Klein Teri E. PubMed
  28. Cytochrome P450 2C9-CYP2C9. Pharmacogenetics and genomics. 2010. Van Booven Derek, Marsh Sharon, McLeod Howard, Carrillo Michelle Whirl, Sangkuhl Katrin, Klein Teri E, Altman Russ B. PubMed
  29. PharmGKB very important pharmacogene: SLCO1B1. Pharmacogenetics and genomics. 2010. Oshiro Connie, Mangravite Lara, Klein Teri, Altman Russ. PubMed
  30. PharmGKB summary: very important pharmacogene information for angiotensin-converting enzyme. Pharmacogenetics and genomics. 2010. Thorn Caroline F, Klein Teri E, Altman Russ B. PubMed
  31. Very important pharmacogene summary ADRB2. Pharmacogenetics and genomics. 2010. Litonjua Augusto A, Gong Li, Duan Qing Ling, Shin Jaekyu, Moore Mariellen J, Weiss Scott T, Johnson Julie A, Klein Teri E, Altman Russ B. PubMed
  32. Cytochrome P450 2D6. Pharmacogenetics and genomics. 2009. Owen Ryan P, Sangkuhl Katrin, Klein Teri E, Altman Russ B. PubMed
  33. Very important pharmacogene summary: sulfotransferase 1A1. Pharmacogenetics and genomics. 2009. Hildebrandt Michelle, Adjei Araba, Weinshilboum Richard, Johnson Julie A, Berlin Dorit S, Klein Teri E, Altman Russ B. PubMed

Other Publications: 191

  1. Pharmacogenetic Allele Nomenclature: International Workgroup Recommendations for Test Result Reporting. Clinical pharmacology and therapeutics. 2015. Kalman Lisa V, Agúndez José A G, Appell Malin Lindqvist, Black John Logan, Bell Gillian C, Boukouvala Sotiria, Bruckner Carsten, Bruford Elspeth, Caudle Kelly, Coulthard Sally, Daly Ann K, Del Tredici Andria L, den Dunnen Johan T, Drozda Katarzyna, Everts Robin, Flockhart David, Freimuth Robert, Gaedigk Andrea, Hachad Houda, Hartshorne Toinette, Ingelman-Sundberg Magnus, Klein Teri E, Lauschke Volker M, Maglott Donna R, McLeod Howard L, McMillin Gwendolyn A, Meyer Urs A, Müller Daniel J, Nickerson Deborah A, Oetting William S, Pacanowski Michael, Pratt Victoria M, Relling Mary V, Roberts Ali, Rubinstein Wendy S, Sangkuhl Katrin, Schwab Matthias, Scott Stuart A, Sim Sarah C, Thirumaran Ranjit K, Toji Lorraine H, Tyndale Rachel, van Schaik Ron H N, Whirl-Carrillo Michelle, Yeo Kiang-Teck J, Zanger Ulrich M. PubMed
  2. Enabling the curation of your pharmacogenetic study. Clinical pharmacology and therapeutics. 2015. McDonagh Em, Whirl-Carrillo M, Altman Rb, Klein Te. PubMed
  3. Evidence synthesis and guideline development in genomic medicine: current status and future prospects. Genetics in medicine : official journal of the American College of Medical Genetics. 2015. Schully Sheri D, Lam Tram Kim, Dotson W David, Chang Christine Q, Aronson Naomi, Birkeland Marian L, Brewster Stephanie Jo, Boccia Stefania, Buchanan Adam H, Calonge Ned, Calzone Kathleen, Djulbegovic Benjamin, Goddard Katrina A B, Klein Roger D, Klein Teri E, Lau Joseph, Long Rochelle, Lyman Gary H, Morgan Rebecca L, Palmer Christina G S, Relling Mary V, Rubinstein Wendy S, Swen Jesse J, Terry Sharon F, Williams Marc S, Khoury Muin J. PubMed
  4. A twentieth anniversary tribute to PSB. Pacific Symposium on Biocomputing. Pacific Symposium on Biocomputing. 2015. Hewett Darla, Whirl-Carrillo Michelle, Hunter Lawrence E, Altman Russ B, Klein Teri E. PubMed
  5. The International SSRI Pharmacogenomics Consortium (ISPC): a genome-wide association study of antidepressant treatment response. Translational psychiatry. 2015. Biernacka J M, Sangkuhl K, Jenkins G, Whaley R M, Barman P, Batzler A, Altman R B, Arolt V, Brockmöller J, Chen C H, Domschke K, Hall-Flavin D K, Hong C J, Illi A, Ji Y, Kampman O, Kinoshita T, Leinonen E, Liou Y J, Mushiroda T, Nonen S, Skime M K, Wang L, Baune B T, Kato M, Liu Y L, Praphanphoj V, Stingl J C, Tsai S J, Kubo M, Klein T E, Weinshilboum R. PubMed
  6. Genetic determinants of age-related macular degeneration in diverse populations from the PAGE study. Investigative ophthalmology & visual science. 2014. Restrepo Nicole A, Spencer Kylee L, Goodloe Robert, Garrett Tiana A, Heiss Gerardo, Bůžková Petra, Jorgensen Neal, Jensen Richard A, Matise Tara C, Hindorff Lucia A, Klein Barbara E K, Klein Ronald, Wong Tien Y, Cheng Ching-Yu, Cornes Belinda K, Tai E-Shyong, Ritchie Marylyn D, Haines Jonathan L, Crawford Dana C. PubMed
  7. Interpreting the CYP2D6 results from the International Tamoxifen Pharmacogenetics Consortium. Clinical pharmacology and therapeutics. 2014. Province M A, Altman R B, Klein T E. PubMed
  8. Genetic variant in folate homeostasis associated with lower warfarin dose in African Americans. Blood. 2014. Daneshjou Roxana, Gamazon Eric R, Burkley Ben, Cavallari Larisa H, Johnson Julie A, Klein Teri E, Limdi Nita, Hillenmeyer Sara, Percha Bethany, Karczewski Konrad J, Langaee Taimour, Patel Shitalben R, Bustamante Carlos D, Altman Russ B, Perera Minoli A. PubMed
  9. Genotype-guided dosing of vitamin K antagonists. The New England journal of medicine. 2014. Daneshjou Roxana, Klein Teri E, Altman Russ B. PubMed
  10. Incorporation of Pharmacogenomics into Routine Clinical Practice: the Clinical Pharmacogenetics Implementation Consortium (CPIC) Guideline Development Process. Current drug metabolism. 2014. Caudle Kelly E, Klein Teri E, Hoffman James M, Müller Daniel J, Whirl-Carrillo Michelle, Gong Li, McDonagh Ellen M, Sangkuhl Katrin, Thorn Caroline F, Schwab Matthias, Agunder Jose A G, Freimuth Robert R, Huser Vojtech, Lee Ming Ta Michael, Iwuchukwu Otito F, Crews Kristine R, Scott Stuart A, Wadelius Mia, Swen Jesse J, Tyndale Rachel F, Stein C Michael, Roden Dan, Relling Mary V, Williams Marc S, Johnson Samuel G. PubMed
  11. Re: CYP2D6 Genotyping and the Use of Tamoxifen in Breast Cancer. Journal of the National Cancer Institute. 2014. Province Michael A, Klein Teri E, On behalf of the International Tamoxifen Pharmacogenomics Consortium. PubMed
  12. Path-scan: a reporting tool for identifying clinically actionable variants. Pacific Symposium on Biocomputing. Pacific Symposium on Biocomputing. 2014. Daneshjou Roxana, Zappala Zachary, Kukurba Kim, Boyle Sean M, Ormond Kelly E, Klein Teri E, Snyder Michael, Bustamante Carlos D, Altman Russ B, Montgomery Stephen B. PubMed
  13. CYP2D6 Genotype and Adjuvant Tamoxifen: Meta-analysis of Heterogeneous Study Populations. Clinical pharmacology and therapeutics. 2013. Province Michael A, Goetz Matthew P, Brauch Hiltrud, Flockhart David A, Hebert Joan M, Whaley Ryan, Suman Vera J, Schroth Werner, Winter Stefan, Zembutsu Hitoshi, Mushiroda Taisei, Newman William G, Michael Lee Ming-Ta, Ambrosone Christine B, Beckmann Matthias W, Choi Ji-Yeob, Dieudonné Anne-Sophie, Fasching Peter A, Ferraldeschi Roberta, Gong Li, Haschke-Becher Elisabeth, Howell Anthony, Jordan Lee B, Hamann Ute, Kiyotani Kazuma, Krippl Peter, Lambrechts Diether, Latif Ayse, Langsenlehner Uwe, Lorizio Wendy, Neven Patrick, Nguyen Anne T, Park Byeong-Woo, Purdie Colin A, Quinlan Philip, Renner Wilifried, Schmidt Marcus, Schwab Matthias, Shin Jae-Gook, Stingl Julia C, Wegman Pia, Wingren Sten, Wu Alan H B, Ziv Elad, Zirpoli Gary, Thompson Alastair M, Jordan V Craig, Nakamura Yusuke, Altman Russ B, Ames Matthew M, Weinshilboum Richard M, Eichelbaum Michel, Ingle James N, Klein Teri E. PubMed
  14. Pharmacogenetics of warfarin: challenges and opportunities. Journal of human genetics. 2013. Lee Ming Ta Michael, Klein Teri E. PubMed
  15. Improving data and knowledge management to better integrate health care and research. Journal of internal medicine. 2013. Cases M, Furlong L I, Albanell J, Altman R B, Bellazzi R, Boyer S, Brand A, Brookes A J, Brunak S, Clark T W, Gea J, Ghazal P, Graf N, Guigó R, Klein T E, López-Bigas N, Maojo V, Mons B, Musen M, Oliveira J L, Rowe A, Ruch P, Shabo A, Shortliffe E H, Valencia A, van der Lei J, Mayer M A, Sanz F. PubMed
  16. Genetic variants associated with warfarin dose in African-American individuals: a genome-wide association study. Lancet. 2013. Perera Minoli A, Cavallari Larisa H, Limdi Nita A, Gamazon Eric R, Konkashbaev Anuar, Daneshjou Roxana, Pluzhnikov Anna, Crawford Dana C, Wang Jelai, Liu Nianjun, Tatonetti Nicholas, Bourgeois Stephane, Takahashi Harumi, Bradford Yukiko, Burkley Benjamin M, Desnick Robert J, Halperin Jonathan L, Khalifa Sherief I, Langaee Taimour Y, Lubitz Steven A, Nutescu Edith A, Oetjens Matthew, Shahin Mohamed H, Patel Shitalben R, Sagreiya Hersh, Tector Matthew, Weck Karen E, Rieder Mark J, Scott Stuart A, Wu Alan Hb, Burmester James K, Wadelius Mia, Deloukas Panos, Wagner Michael J, Mushiroda Taisei, Kubo Michiaki, Roden Dan M, Cox Nancy J, Altman Russ B, Klein Teri E, Nakamura Yusuke, Johnson Julie A. PubMed
  17. Challenges in the pharmacogenomic annotation of whole genomes. Clinical pharmacology and therapeutics. 2013. Altman Russ B, Whirl-Carrillo Michelle, Klein Teri E. PubMed
  18. Clinical Implementation of Pharmacogenetics: More than One Gene at a Time. Clinical pharmacology and therapeutics. 2013. Johnson J A, Klein T E, Relling M V. PubMed
  19. The Pharmacogenomics Research Network Translational Pharmacogenetics Program: Overcoming Challenges of Real-World Implementation. Clinical pharmacology and therapeutics. 2013. Shuldiner Alan R, Relling Mary V, Peterson Josh F, Hicks Kevin, Freimuth Robert R, Sadee Wolfgang, Pereira Naveen L, Roden Dan M, Johnson Julie A, Klein Teri E. PubMed
  20. Web-scale pharmacovigilance: listening to signals from the crowd. Journal of the American Medical Informatics Association : JAMIA. 2013. White Ryen W, Tatonetti Nicholas P, Shah Nigam H, Altman Russ B, Horvitz Eric. PubMed
  21. Data re-identification: societal safeguards. Science (New York, N.Y.). 2013. Altman Russ B, Clayton Ellen Wright, Kohane Isaac S, Malin Bradley A, Roden Dan M. PubMed
  22. Nomenclature for alleles of the thiopurine methyltransferase gene. Pharmacogenetics and genomics. 2013. Appell Malin L, Berg Jonathan, Duley John, Evans William, Kennedy Martin A, Lennard Lynne, Marinaki Tony, McLeod Howard L, Relling Mary V, Schaeffeler Elke, Schwab Matthias, Weinshilboum Richard, Yeoh Allen E J, McDonagh Ellen M, Hebert Joan M, Klein Teri E, Coulthard Sally A. PubMed
  23. Personal genomic measurements: the opportunity for information integration. Clinical pharmacology and therapeutics. 2013. Altman R B. PubMed
  24. Pathway analysis of genome-wide data improves warfarin dose prediction. BMC genomics. 2013. Daneshjou Roxana, Tatonetti Nicholas P, Karczewski Konrad J, Sagreiya Hersh, Bourgeois Stephane, Drozda Katarzyna, Burmester James K, Tsunoda Tatsuhiko, Nakamura Yusuke, Kubo Michiaki, Tector Matthew, Limdi Nita A, Cavallari Larisa H, Perera Minoli, Johnson Julie A, Klein Teri E, Altman Russ B. PubMed
  25. PharmGKB: the Pharmacogenomics Knowledge Base. Methods in molecular biology (Clifton, N.J.). 2013. Thorn Caroline F, Klein Teri E, Altman Russ B. PubMed
  26. Introduction to translational bioinformatics collection. PLoS computational biology. 2012. Altman Russ B. PubMed
  27. Pharmacogenomics knowledge for personalized medicine. Clinical pharmacology and therapeutics. 2012. Whirl-Carrillo M, McDonagh E M, Hebert J M, Gong L, Sangkuhl K, Thorn C F, Altman R B, Klein T E. PubMed
  28. Implementing Personalized Medicine: Development of a Cost-Effective Customized Pharmacogenetics Genotyping Array. Clinical pharmacology and therapeutics. 2012. Johnson J A, Burkley B M, Langaee T Y, Clare-Salzler M J, Klein T E, Altman R B. PubMed
  29. Translational bioinformatics: linking the molecular world to the clinical world. Clinical pharmacology and therapeutics. 2012. Altman R B. PubMed
  30. Clopidogrel: a case for indication-specific pharmacogenetics. Clinical pharmacology and therapeutics. 2012. Johnson J A, Roden D M, Lesko L J, Ashley E, Klein T E, Shuldiner A R. PubMed
  31. Very important pharmacogene summary for VDR. Pharmacogenetics and genomics. 2012. Poon Audrey H, Gong Li, Brasch-Andersen Charlotte, Litonjua Augusto A, Raby Benjamin A, Hamid Qutayba, Laprise Catherine, Weiss Scott T, Altman Russ B, Klein Teri E. PubMed
  32. Personal omics profiling reveals dynamic molecular and medical phenotypes. Cell. 2012. Chen Rui, Mias George I, Li-Pook-Than Jennifer, Jiang Lihua, Lam Hugo Y K, Chen Rong, Miriami Elana, Karczewski Konrad J, Hariharan Manoj, Dewey Frederick E, Cheng Yong, Clark Michael J, Im Hogune, Habegger Lukas, Balasubramanian Suganthi, O'Huallachain Maeve, Dudley Joel T, Hillenmeyer Sara, Haraksingh Rajini, Sharon Donald, Euskirchen Ghia, Lacroute Phil, Bettinger Keith, Boyle Alan P, Kasowski Maya, Grubert Fabian, Seki Scott, Garcia Marco, Whirl-Carrillo Michelle, Gallardo Mercedes, Blasco Maria A, Greenberg Peter L, Snyder Phyllis, Klein Teri E, Altman Russ B, Butte Atul J, Ashley Euan A, Gerstein Mark, Nadeau Kari C, Tang Hua, Snyder Michael. PubMed
  33. From pharmacogenomic knowledge acquisition to clinical applications: the PharmGKB as a clinical pharmacogenomic biomarker resource. Biomarkers in medicine. 2011. McDonagh Ellen M, Whirl-Carrillo Michelle, Garten Yael, Altman Russ B, Klein Teri E. PubMed
  34. Using ODIN for a PharmGKB revalidation experiment. Database : the journal of biological databases and curation. 2012. Rinaldi Fabio, Clematide Simon, Garten Yael, Whirl-Carrillo Michelle, Gong Li, Hebert Joan M, Sangkuhl Katrin, Thorn Caroline F, Klein Teri E, Altman Russ B. PubMed
  35. Using multiple microenvironments to find similar ligand-binding sites: application to kinase inhibitor binding. PLoS computational biology. 2011. Liu Tianyun, Altman Russ B. PubMed
  36. A new disease-specific machine learning approach for the prediction of cancer-causing missense variants. Genomics. 2011. Capriotti Emidio, Altman Russ B. PubMed
  37. Phased whole-genome genetic risk in a family quartet using a major allele reference sequence. PLoS genetics. 2011. Dewey Frederick E, Chen Rong, Cordero Sergio P, Ormond Kelly E, Caleshu Colleen, Karczewski Konrad J, Whirl-Carrillo Michelle, Wheeler Matthew T, Dudley Joel T, Byrnes Jake K, Cornejo Omar E, Knowles Joshua W, Woon Mark, Sangkuhl Katrin, Gong Li, Thorn Caroline F, Hebert Joan M, Capriotti Emidio, David Sean P, Pavlovic Aleksandra, West Anne, Thakuria Joseph V, Ball Madeleine P, Zaranek Alexander W, Rehm Heidi L, Church George M, West John S, Bustamante Carlos D, Snyder Michael, Altman Russ B, Klein Teri E, Butte Atul J, Ashley Euan A. PubMed
  38. Cooperative transcription factor associations discovered using regulatory variation. Proceedings of the National Academy of Sciences of the United States of America. 2011. Karczewski Konrad J, Tatonetti Nicholas P, Landt Stephen G, Yang Xinqiong, Slifer Teri, Altman Russ B, Snyder Michael. PubMed
  39. CPIC: Clinical Pharmacogenetics Implementation Consortium of the Pharmacogenomics Research Network. Clinical pharmacology and therapeutics. 2011. Relling M V, Klein T E. PubMed
  40. Pharmacogenomics: "noninferiority" is sufficient for initial implementation. Clinical pharmacology and therapeutics. 2011. Altman R B. PubMed
  41. Databases in the area of pharmacogenetics. Human mutation. 2011. Sim Sarah C, Altman Russ B, Ingelman-Sundberg Magnus. PubMed
  42. Improving the prediction of disease-related variants using protein three-dimensional structure. BMC bioinformatics. 2011. Capriotti Emidio, Altman Russ B. PubMed
  43. Using text to build semantic networks for pharmacogenomics. Journal of biomedical informatics. 2010. Coulet Adrien, Shah Nigam H, Garten Yael, Musen Mark, Altman Russ B. PubMed
  44. 2010 translational bioinformatics year in review. Journal of the American Medical Informatics Association : JAMIA. 2011. Altman Russ B, Miller Katharine S. PubMed
  45. Warfarin pharmacogenetics: a single VKORC1 polymorphism is predictive of dose across 3 racial groups. Blood. 2010. Limdi Nita A, Wadelius Mia, Cavallari Larisa, Eriksson Niclas, Crawford Dana C, Lee Ming-Ta M, Chen Chien-Hsiun, Motsinger-Reif Alison, Sagreiya Hersh, Liu Nianjun, Wu Alan H B, Gage Brian F, Jorgensen Andrea, Pirmohamed Munir, Shin Jae-Gook, Suarez-Kurtz Guilherme, Kimmel Stephen E, Johnson Julie A, Klein Teri E, Wagner Michael J, International Warfarin Pharmacogenetics Consortium. PubMed
  46. Challenges in the clinical application of whole-genome sequencing. Lancet. 2010. Ormond Kelly E, Wheeler Matthew T, Hudgins Louanne, Klein Teri E, Butte Atul J, Altman Russ B, Ashley Euan A, Greely Henry T. PubMed
  47. Clinical assessment incorporating a personal genome. Lancet. 2010. Ashley Euan A, Butte Atul J, Wheeler Matthew T, Chen Rong, Klein Teri E, Dewey Frederick E, Dudley Joel T, Ormond Kelly E, Pavlovic Aleksandra, Morgan Alexander A, Pushkarev Dmitry, Neff Norma F, Hudgins Louanne, Gong Li, Hodges Laura M, Berlin Dorit S, Thorn Caroline F, Sangkuhl Katrin, Hebert Joan M, Woon Mark, Sagreiya Hersh, Whaley Ryan, Knowles Joshua W, Chou Michael F, Thakuria Joseph V, Rosenbaum Abraham M, Zaranek Alexander Wait, Church George M, Greely Henry T, Quake Stephen R, Altman Russ B. PubMed
  48. DNATwist: a Web-based tool for teaching middle and high school students about pharmacogenomics. Clinical pharmacology and therapeutics. 2010. Berlin D S, Person M G, Mittal A, Oppezzo M A, Chin D B, Starr B, Klein T E, Schwartz D L, Altman R B. PubMed
  49. Pharmacogenomics and bioinformatics: PharmGKB. Pharmacogenomics. 2010. Thorn Caroline F, Klein Teri E, Altman Russ B. PubMed
  50. Improving the prediction of pharmacogenes using text-derived drug-gene relationships. Pacific Symposium on Biocomputing. Pacific Symposium on Biocomputing. 2010. Garten Yael, Tatonetti Nicholas P, Altman Russ B. PubMed
  51. Generating genome-scale candidate gene lists for pharmacogenomics. Clinical pharmacology and therapeutics. 2009. Hansen N T, Brunak S, Altman R B. PubMed
  52. New feature: pathways and important genes from PharmGKB. Pharmacogenetics and genomics. 2009. Eichelbaum Michel, Altman Russ B, Ratain Mark, Klein Teri E. PubMed
  53. Estimation of the warfarin dose with clinical and pharmacogenetic data. The New England journal of medicine. 2009. International Warfarin Pharmacogenetics Consortium, Klein T E, Altman R B, Eriksson N, Gage B F, Kimmel S E, Lee M-T M, Limdi N A, Page D, Roden D M, Wagner M J, Caldwell M D, Johnson J A. PubMed
  54. PharmGKB: an integrated resource of pharmacogenomic data and knowledge. Current protocols in bioinformatics / editoral board, Andreas D. Baxevanis ... [et al.]. 2008. Gong Li, Owen Ryan P, Gor Winston, Altman Russ B, Klein Teri E. PubMed
  55. PharmGKB and the International Warfarin Pharmacogenetics Consortium: the changing role for pharmacogenomic databases and single-drug pharmacogenetics. Human mutation. 2008. Owen Ryan P, Altman Russ B, Klein Teri E. PubMed
  56. An XML-based interchange format for genotype-phenotype data. Human mutation. 2008. Whirl-Carrillo M, Woon M, Thorn C F, Klein T E, Altman R B. PubMed
  57. The pharmacogenetics and pharmacogenomics knowledge base: accentuating the knowledge. Nucleic acids research. 2008. Hernandez-Boussard Tina, Whirl-Carrillo Michelle, Hebert Joan M, Gong Li, Owen Ryan, Gong Mei, Gor Winston, Liu Feng, Truong Chuong, Whaley Ryan, Woon Mark, Zhou Tina, Altman Russ B, Klein Teri E. PubMed
  58. Lack of association between common polymorphisms in UGT1A9 and gene expression and activity. Drug metabolism and disposition: the biological fate of chemicals. 2007. Ramírez Jacqueline, Liu Wanqing, Mirkov Snezana, Desai Apurva A, Chen Peixian, Das Soma, Innocenti Federico, Ratain Mark J. PubMed
  59. PharmGKB: understanding the effects of individual genetic variants. Drug metabolism reviews. 2008. Sangkuhl Katrin, Berlin Dorit S, Altman Russ B, Klein Teri E. PubMed
  60. Pharmacogenetics of deoxycytidine kinase: identification and characterization of novel genetic variants. The Journal of pharmacology and experimental therapeutics. 2007. Lamba Jatinder K, Crews Kristine, Pounds Stanley, Schuetz Erin G, Gresham Jessica, Gandhi Varsha, Plunkett William, Rubnitz Jeffrey, Ribeiro Raul. PubMed
  61. Relationship of EGFR mutations, expression, amplification, and polymorphisms to epidermal growth factor receptor inhibitors in the NCI60 cell lines. Clinical cancer research : an official journal of the American Association for Cancer Research. 2007. Liu Wanqing, Wu Xiaolin, Zhang Wei, Montenegro Raquel C, Fackenthal Donna Lee, Spitz Jared A, Huff Lyn Mickley, Innocenti Federico, Das Soma, Cook Edwin H, Cox Nancy J, Bates Susan E, Ratain Mark J. PubMed
  62. The education potential of the pharmacogenetics and pharmacogenomics knowledge base (PharmGKB). Clinical pharmacology and therapeutics. 2007. Owen R P, Klein T E, Altman R B. PubMed
  63. Genome scan implicates adhesion biological pathways in secondary leukemia. Leukemia : official journal of the Leukemia Society of America, Leukemia Research Fund, U.K. 2007. Hartford C, Yang W, Cheng C, Fan Y, Liu W, Treviño L, Pounds S, Neale G, Raimondi S C, Bogni A, Dolan M E, Pui C-H, Relling M V. PubMed
  64. Identification of genetic variants contributing to cisplatin-induced cytotoxicity by use of a genomewide approach. American journal of human genetics. 2007. Huang R Stephanie, Duan Shiwei, Shukla Sunita J, Kistner Emily O, Clark Tyson A, Chen Tina X, Schweitzer Anthony C, Blume John E, Dolan M Eileen. PubMed
  65. UGT1A1*28 genotype affects the in-vitro glucuronidation of thyroxine in human livers. Pharmacogenetics and genomics. 2007. Yoder Graber Andrea L, Ramírez Jacqueline, Innocenti Federico, Ratain Mark J. PubMed
  66. Mapping genes that contribute to daunorubicin-induced cytotoxicity. Cancer research. 2007. Duan Shiwei, Bleibel Wasim K, Huang Rong Stephanie, Shukla Sunita J, Wu Xiaolin, Badner Judith A, Dolan M Eileen. PubMed
  67. A comparison of the pharmacokinetics and pharmacodynamics of docetaxel between African-American and Caucasian cancer patients: CALGB 9871. Clinical cancer research : an official journal of the American Association for Cancer Research. 2007. Lewis Lionel D, Miller Antonius A, Rosner Gary L, Dowell Jonathan E, Valdivieso Manuel, Relling Mary V, Egorin Merrill J, Bies Robert R, Hollis Donna R, Levine Ellis G, Otterson Gregory A, Millard Frederick, Ratain Mark J, Cancer and Leukemia Group B. PubMed
  68. A functional genetic polymorphism on human carbonyl reductase 1 (CBR1 V88I) impacts on catalytic activity and NADPH binding affinity. Drug metabolism and disposition: the biological fate of chemicals. 2007. Gonzalez-Covarrubias Vanessa, Ghosh Debashis, Lakhman Sukhwinder S, Pendyala Lakshmi, Blanco Javier G. PubMed
  69. Gender-specific differences in expression in human lymphoblastoid cell lines. Pharmacogenetics and genomics. 2007. Zhang Wei, Bleibel Wasim K, Roe Cheryl A, Cox Nancy J, Eileen Dolan M. PubMed
  70. A genome-wide approach to identify genetic variants that contribute to etoposide-induced cytotoxicity. Proceedings of the National Academy of Sciences of the United States of America. 2007. Huang R Stephanie, Duan Shiwei, Bleibel Wasim K, Kistner Emily O, Zhang Wei, Clark Tyson A, Chen Tina X, Schweitzer Anthony C, Blume John E, Cox Nancy J, Dolan M Eileen. PubMed
  71. Ancestry and pharmacogenetics of antileukemic drug toxicity. Blood. 2007. Kishi Shinji, Cheng Cheng, French Deborah, Pei Deqing, Das Soma, Cook Edwin H, Hijiya Nobuko, Rizzari Carmelo, Rosner Gary L, Frudakis Tony, Pui Ching-Hon, Evans William E, Relling Mary V. PubMed
  72. Differential effects of targeted disruption of thiopurine methyltransferase on mercaptopurine and thioguanine pharmacodynamics. Cancer research. 2007. Hartford Christine, Vasquez Erick, Schwab Matthias, Edick Mathew J, Rehg Jerold E, Grosveld Gerard, Pui Ching-Hon, Evans William E, Relling Mary V. PubMed
  73. Using HapMap tools in pharmacogenomic discovery: the thiopurine methyltransferase polymorphism. Clinical pharmacology and therapeutics. 2007. Jones T S, Yang W, Evans W E, Relling M V. PubMed
  74. Effect of the alpha2C-adrenoreceptor deletion322-325 variant on sympathetic activity and cardiovascular measures in healthy subjects. Journal of hypertension. 2007. Kurnik Daniel, Muszkat Mordechai, Friedman Eitan A, Sofowora Gbenga G, Diedrich André, Xie Hong-Guang, Harris Paul A, Choi Leena, Wood Alastair J J, Stein C Michael. PubMed
  75. The pharmacogenetics research network: from SNP discovery to clinical drug response. Clinical pharmacology and therapeutics. 2007. Giacomini K M, Brett C M, Altman R B, Benowitz N L, Dolan M E, Flockhart D A, Johnson J A, Hayes D F, Klein T, Krauss R M, Kroetz D L, McLeod H L, Nguyen A T, Ratain M J, Relling M V, Reus V, Roden D M, Schaefer C A, Shuldiner A R, Skaar T, Tantisira K, Tyndale R F, Wang L, Weinshilboum R M, Weiss S T, Zineh I, Pharmacogenetics Research Network. PubMed
  76. Biomedical informatics training at Stanford in the 21st century. Journal of biomedical informatics. 2007. Altman Russ B, Klein Teri E. PubMed
  77. The PharmGKB: integration, aggregation, and annotation of pharmacogenomic data and knowledge. Clinical pharmacology and therapeutics. 2007. Hodge A E, Altman R B, Klein T E. PubMed
  78. Extracting subject demographic information from abstracts of randomized clinical trial reports. Studies in health technology and informatics. 2007. Xu Rong, Garten Yael, Supekar Kaustubh S, Das Amar K, Altman Russ B, Garber Alan M. PubMed
  79. Pharmacogenomics: challenges and opportunities. Annals of internal medicine. 2006. Roden Dan M, Altman Russ B, Benowitz Neal L, Flockhart David A, Giacomini Kathleen M, Johnson Julie A, Krauss Ronald M, McLeod Howard L, Ratain Mark J, Relling Mary V, Ring Huijun Z, Shuldiner Alan R, Weinshilboum Richard M, Weiss Scott T, Pharmacogenetics Research Network. PubMed
  80. Robust estimation of the false discovery rate. Bioinformatics (Oxford, England). 2006. Pounds Stan, Cheng Cheng. PubMed
  81. Pharmacogenetic characteristics of indinavir, zidovudine, and lamivudine therapy in HIV-infected adults: a pilot study. Journal of acquired immune deficiency syndromes (1999). 2006. Anderson Peter L, Lamba Jatinder, Aquilante Christina L, Schuetz Erin, Fletcher Courtney V. PubMed
  82. The incidentalome: a threat to genomic medicine. JAMA : the journal of the American Medical Association. 2006. Kohane Isaac S, Masys Daniel R, Altman Russ B. PubMed
  83. Higher activity of polymorphic NAD(P)H:quinone oxidoreductase in liver cytosols from blacks compared to whites. Toxicology letters. 2006. Covarrubias Vanessa Gonzalez, Lakhman Sukhwinder S, Forrest Alan, Relling Mary V, Blanco Javier G. PubMed
  84. Increased CYP3A4 copy number in TONG/HCC cells but not in DNA from other humans. Pharmacogenetics and genomics. 2006. Lamba Jatinder K, Chen Xin, Lan Lu-Bin, Kim Jin Woo, Wei Wang Xin, Relling Mary V, Kazuto Yasuda, Watkins Paul B, Strom Stephen, Sun Daxi, Schuetz John D, Schuetz Erin G. PubMed
  85. MDR1 genotype is associated with hepatic cytochrome P450 3A4 basal and induction phenotype. Clinical pharmacology and therapeutics. 2006. Lamba Jatinder, Strom Stephen, Venkataramanan Raman, Thummel Kenneth E, Lin Yvonne S, Liu Wei, Cheng Cheng, Lamba Vishal, Watkins Paul B, Schuetz Erin. PubMed
  86. Choosing SNPs using feature selection. Journal of bioinformatics and computational biology. 2006. Phuong Tu Minh, Lin Zhen, Altman Russ B. PubMed
  87. Variations in the alpha2A-adrenergic receptor gene and their functional effects. Clinical pharmacology and therapeutics. 2006. Kurnik Daniel, Muszkat Mordechai, Li Chun, Sofowora Gbenga G, Solus Joseph, Xie Hong-Guang, Harris Paul A, Jiang Lan, McMunn Chara, Ihrie Patrick, Dawson Elliott P, Williams Scott M, Wood Alastair J J, Stein C Michael. PubMed
  88. G2677T and C3435T genotype and haplotype are associated with hepatic ABCB1 (MDR1) expression. Journal of clinical pharmacology. 2006. Song Pengfei, Lamba Jatinder K, Zhang Lijun, Schuetz Erin, Shukla Nikhil, Meibohm Bernd, Yates Charles R. PubMed
  89. Pharmacogenomics: The relevance of emerging genotyping technologies. MLO: medical laboratory observer. 2006. Hernandez-Boussard Tina, Klein Teri E, Altman Russ B. PubMed
  90. Gene variants in noncoding regions and their possible consequences. Pharmacogenomics. 2006. Wang Guang-Ji, Yang Ping, Xie Hong-Guang. PubMed
  91. Genome-wide approach to identify risk factors for therapy-related myeloid leukemia. Leukemia : official journal of the Leukemia Society of America, Leukemia Research Fund, U.K. 2006. Bogni A, Cheng C, Liu W, Yang W, Pfeffer J, Mukatira S, French D, Downing J R, Pui C-H, Relling M V. PubMed
  92. Study of the genetic determinants of UGT1A1 inducibility by phenobarbital in cultured human hepatocytes. Pharmacogenetics and genomics. 2006. Ramírez Jacqueline, Komoroski Bernard J, Mirkov Snezana, Graber Andrea Yoder, Fackenthal Donna Lee, Schuetz Erin G, Das Soma, Ratain Mark J, Innocenti Federico, Strom Stephen C. PubMed
  93. The Eighth International Childhood Acute Lymphoblastic Leukemia Workshop ('Ponte di legno meeting') report: Vienna, Austria, April 27-28, 2005. Leukemia : official journal of the Leukemia Society of America, Leukemia Research Fund, U.K. 2006. Gadner H, Masera G, Schrappe M, Eden T, Benoit Y, Harrison C, Nachman J, Pui C H. PubMed
  94. Variation in oral clearance of saquinavir is predicted by CYP3A5*1 genotype but not by enterocyte content of cytochrome P450 3A5. Clinical pharmacology and therapeutics. 2005. Mouly Stéphane J, Matheny Chris, Paine Mary F, Smith Glenn, Lamba Jatinder, Lamba Vishal, Pusek Susan N, Schuetz Erin G, Stewart Paul W, Watkins Paul B. PubMed
  95. Development of FuGO: an ontology for functional genomics investigations. Omics : a journal of integrative biology. 2006. Whetzel Patricia L, Brinkman Ryan R, Causton Helen C, Fan Liju, Field Dawn, Fostel Jennifer, Fragoso Gilberto, Gray Tanya, Heiskanen Mervi, Hernandez-Boussard Tina, Morrison Norman, Parkinson Helen, Rocca-Serra Philippe, Sansone Susanna-Assunta, Schober Daniel, Smith Barry, Stevens Robert, Stoeckert Christian J, Taylor Chris, White Joe, Wood Andrew, FuGO Working Group. PubMed
  96. Integrating large-scale genotype and phenotype data. Omics : a journal of integrative biology. 2006. Hernandez-Boussard Tina, Woon Mark, Klein Teri E, Altman Russ B. PubMed
  97. ADME transcriptome in Hispanic versus White donor livers: evidence of a globally enhanced NR1I3 (CAR, constitutive androstane receptor) gene signature in Hispanics. Xenobiotica; the fate of foreign compounds in biological systems. 2006. Finkelstein D, Lamba V, Assem M, Rengelshausen J, Yasuda K, Strom S, Schuetz E. PubMed
  98. Placental transfer of antiretroviral drugs. Clinical pharmacology and therapeutics. 2005. Marzolini Catia, Kim Richard B. PubMed
  99. The seventh international childhood acute lymphoblastic leukemia workshop report: Palermo, Italy, January 29--30, 2005. Leukemia : official journal of the Leukemia Society of America, Leukemia Research Fund, U.K. 2005. Aricó M, Baruchel A, Bertrand Y, Biondi A, Conter V, Eden T, Gadner H, Gaynon P, Horibe K, Hunger S P, Janka-Schaub G, Masera G, Nachman J, Pieters R, Schrappe M, Schmiegelow K, Valsecchi M G, Pui C-H. PubMed
  100. Evolution of the pregnane x receptor: adaptation to cross-species differences in biliary bile salts. Molecular endocrinology (Baltimore, Md.). 2005. Krasowski Matthew D, Yasuda Kazuto, Hagey Lee R, Schuetz Erin G. PubMed
  101. Pharmacogenetics of outcome in children with acute lymphoblastic leukemia. Blood. 2005. Rocha Jose Claudio C, Cheng Cheng, Liu Wei, Kishi Shinji, Das Soma, Cook Edwin H, Sandlund John T, Rubnitz Jeffrey, Ribeiro Raul, Campana Dario, Pui Ching-Hon, Evans William E, Relling Mary V. PubMed
  102. Global gene expression as a function of germline genetic variation. Human molecular genetics. 2005. French Deborah, Wilkinson Mark R, Yang Wenjian, de Chaisemartin Luc, Cook Edwin H, Das Soma, Ratain Mark J, Evans William E, Downing James R, Pui Ching-Hon, Relling Mary V. PubMed
  103. Variation in the alpha2B-adrenergic receptor gene (ADRA2B) and its relationship to vascular response in vivo. Pharmacogenetics and genomics. 2005. Muszkat Mordechai, Kurnik Daniel, Solus Joseph, Sofowora Gbenga G, Xie Hong-Guang, Jiang Lan, McMunn Chara, Ihrie Patrick, Harris James R, Dawson Elliott P, Williams Scott M, Wood Alastair J J, Stein C Michael. PubMed
  104. Pharmacogenetics and rheumatology: Molecular mechanisms contributing to variability in drug response. Arthritis and rheumatism. 2005. Asanuma Yu, Xie Hong-Guang, Stein C Michael. PubMed
  105. Haplotypes of variants in the UDP-glucuronosyltransferase1A9 and 1A1 genes. Pharmacogenetics and genomics. 2005. Innocenti Federico, Liu Wanqing, Chen Peixian, Desai Apurva A, Das Soma, Ratain Mark J. PubMed
  106. Identification of genes associated with chemotherapy crossresistance and treatment response in childhood acute lymphoblastic leukemia. Cancer cell. 2005. Lugthart Sanne, Cheok Meyling H, den Boer Monique L, Yang Wenjian, Holleman Amy, Cheng Cheng, Pui Ching-Hon, Relling Mary V, Janka-Schaub Gritta E, Pieters Rob, Evans William E. PubMed
  107. Use of CEPH and non-CEPH lymphoblast cell lines in pharmacogenetic studies. Pharmacogenomics. 2005. Shukla Sunita J, Dolan M Eileen. PubMed
  108. Polymorphisms in human organic anion-transporting polypeptide 1A2 (OATP1A2): implications for altered drug disposition and central nervous system drug entry. The Journal of biological chemistry. 2005. Lee Wooin, Glaeser Hartmut, Smith L Harris, Roberts Richard L, Moeckel Gilbert W, Gervasini Guillermo, Leake Brenda F, Kim Richard B. PubMed
  109. Lymphoid gene expression as a predictor of risk of secondary brain tumors. Genes, chromosomes & cancer. 2005. Edick Mathew J, Cheng Cheng, Yang Wenjian, Cheok Meyling, Wilkinson Mark R, Pei Deqing, Evans William E, Kun Larry E, Pui Ching-Hon, Relling Mary V. PubMed
  110. A functional common polymorphism in a Sp1 recognition site of the epidermal growth factor receptor gene promoter. Cancer research. 2005. Liu Wanqing, Innocenti Federico, Wu Michael H, Desai Apurva A, Dolan M Eileen, Cook Edwin H, Ratain Mark J. PubMed
  111. Alpha2B adrenergic receptor 301-303 deletion polymorphism and vascular alpha2 adrenergic receptor response. Pharmacogenetics and genomics. 2005. Muszkat Mordechai, Sofowora Gbenga G, Xie Hong-Guang, Wood Alastair J J, Stein C Michael. PubMed
  112. A statistical approach to scanning the biomedical literature for pharmacogenetics knowledge. Journal of the American Medical Informatics Association : JAMIA. 2005. Rubin Daniel L, Thorn Caroline F, Klein Teri E, Altman Russ B. PubMed
  113. PharmGKB: the pharmacogenetics and pharmacogenomics knowledge base. Methods in molecular biology (Clifton, N.J.). 2005. Thorn Caroline F, Klein Teri E, Altman Russ B. PubMed
  114. Choosing SNPs using feature selection. Proceedings / IEEE Computational Systems Bioinformatics Conference, CSB. IEEE Computational Systems Bioinformatics Conference. 2005. Phuong Tu Minh, Lin Zhen, Altman Russ B. PubMed
  115. Finding haplotype tagging SNPs by use of principal components analysis. American journal of human genetics. 2004. Lin Zhen, Altman Russ B. PubMed
  116. Improved outcome for children with acute lymphoblastic leukemia: results of Total Therapy Study XIIIB at St Jude Children's Research Hospital. Blood. 2004. Pui Ching-Hon, Sandlund John T, Pei Deqing, Campana Dario, Rivera Gaston K, Ribeiro Raul C, Rubnitz Jeffrey E, Razzouk Bassem I, Howard Scott C, Hudson Melissa M, Cheng Cheng, Kun Larry E, Raimondi Susana C, Behm Frederick G, Downing James R, Relling Mary V, Evans William E, Total Therapy Study XIIIB at St Jude Children's Research Hospital. PubMed
  117. Expression of constitutive androstane receptor splice variants in human tissues and their functional consequences. The Journal of pharmacology and experimental therapeutics. 2004. Lamba Jatinder K, Lamba Vishal, Yasuda Kazuto, Lin Yvonne S, Assem Mahfoud, Thompson Emma, Strom Stephen, Schuetz Erin. PubMed
  118. Tools for loading MEDLINE into a local relational database. BMC bioinformatics. 2004. Oliver Diane E, Bhalotia Gaurav, Schwartz Ariel S, Altman Russ B, Hearst Marti A. PubMed
  119. Pharmacogenetic risk factors for osteonecrosis of the hip among children with leukemia. Journal of clinical oncology : official journal of the American Society of Clinical Oncology. 2004. Relling Mary V, Yang Wenjian, Das Soma, Cook Edwin H, Rosner Gary L, Neel Michael, Howard Scott, Ribeiro Raul, Sandlund John T, Pui Ching-Hon, Kaste Sue C. PubMed
  120. CYP2B6, CYP3A4, and CYP2C19 are responsible for the in vitro N-demethylation of meperidine in human liver microsomes. Drug metabolism and disposition: the biological fate of chemicals. 2004. Ramírez Jacqueline, Innocenti Federico, Schuetz Erin G, Flockhart David A, Relling Mary V, Santucci Raymond, Ratain Mark J. PubMed
  121. Determination and analysis of single nucleotide polymorphisms and haplotype structure of the human carboxylesterase 2 gene. Pharmacogenetics. 2004. Wu Michael H, Chen Peixian, Wu Xiaolin, Liu Wanqing, Strom Stephen, Das Soma, Cook Edwin H, Rosner Gary L, Dolan M Eileen. PubMed
  122. Extracting and characterizing gene-drug relationships from the literature. Pharmacogenetics. 2004. Chang Jeffrey T, Altman Russ B. PubMed
  123. QT analysis: a complex answer to a 'simple' problem. Statistics in medicine. 2004. Li Lang, Desai Mehul, Desta Zeruesenay, Flockhart David. PubMed
  124. PXR (NR1I2): splice variants in human tissues, including brain, and identification of neurosteroids and nicotine as PXR activators. Toxicology and applied pharmacology. 2004. Lamba Vishal, Yasuda Kazuto, Lamba Jatinder K, Assem Mahfoud, Davila Julio, Strom Stephen, Schuetz Erin G. PubMed
  125. Beta2-adrenoceptor Thr164Ile polymorphism is associated with markedly decreased vasodilator and increased vasoconstrictor sensitivity in vivo. Pharmacogenetics. 2004. Dishy Victor, Landau Ruth, Sofowora Gbenga G, Xie Hong-Guang, Smiley Richard M, Kim Richard B, Byrne Daniel W, Wood Alastair J J, Stein C Michael. PubMed
  126. Genetics. Genomic research and human subject privacy. Science (New York, N.Y.). 2004. Lin Zhen, Owen Art B, Altman Russ B. PubMed
  127. Heritability and linkage analysis of sensitivity to cisplatin-induced cytotoxicity. Cancer research. 2004. Dolan M Eileen, Newbold Karla G, Nagasubramanian Ramamoorthy, Wu Xiaolin, Ratain Mark J, Cook Edwin H, Badner Judith A. PubMed
  128. Alpha 1A-adrenergic receptor polymorphism and vascular response. Clinical pharmacology and therapeutics. 2004. Sofowora Gbenga G, Dishy Victor, Landau Ruth, Xie Hong-Guang, Prasad Harish C, Byrne Daniel W, Smiley Richard M, Kim Richard B, Wood Alastair J J, Stein C Michael. PubMed
  129. Ponte di Legno Working Group: statement on the right of children with leukemia to have full access to essential treatment and report on the Sixth International Childhood Acute Lymphoblastic Leukemia Workshop. Leukemia : official journal of the Leukemia Society of America, Leukemia Research Fund, U.K. 2004. Pui C-H, Schrappe M, Masera G, Nachman J, Gadner H, Eden O B, Evans W E, Gaynon P, Ponte di Legno Working Group. PubMed
  130. Genetic variants in the UDP-glucuronosyltransferase 1A1 gene predict the risk of severe neutropenia of irinotecan. Journal of clinical oncology : official journal of the American Society of Clinical Oncology. 2004. Innocenti Federico, Undevia Samir D, Iyer Lalitha, Chen Pei Xian, Das Soma, Kocherginsky Masha, Karrison Theodore, Janisch Linda, Ramírez Jacqueline, Rudin Charles M, Vokes Everett E, Ratain Mark J. PubMed
  131. Genetic variability in CYP3A5 and its possible consequences. Pharmacogenomics. 2004. Xie Hong-Guang, Wood Alastair J J, Kim Richard B, Stein C Michael, Wilkinson Grant R. PubMed
  132. Pharmacogenomics of the OATP and OAT families. Pharmacogenomics. 2004. Marzolini Catia, Tirona Rommel G, Kim Richard B. PubMed
  133. Acute lymphoblastic leukemia. The New England journal of medicine. 2004. Pui Ching-Hon, Relling Mary V, Downing James R. PubMed
  134. Recent advances in childhood acute lymphoblastic leukemia. Journal of the Formosan Medical Association = Taiwan yi zhi. 2004. Pui Ching-Hon. PubMed
  135. Ethnicity-dependent polymorphism in Na+-taurocholate cotransporting polypeptide (SLC10A1) reveals a domain critical for bile acid substrate recognition. The Journal of biological chemistry. 2004. Ho Richard H, Leake Brenda F, Roberts Richard L, Lee Wooin, Kim Richard B. PubMed
  136. GAPSCORE: finding gene and protein names one word at a time. Bioinformatics (Oxford, England). 2004. Chang Jeffrey T, Schütze Hinrich, Altman Russ B. PubMed
  137. Effects of prednisone and genetic polymorphisms on etoposide disposition in children with acute lymphoblastic leukemia. Blood. 2004. Kishi Shinji, Yang Wenjian, Boureau Benoit, Morand Stanislas, Das Soma, Chen Peixian, Cook Edwin H, Rosner Gary L, Schuetz Erin, Pui Ching-Hon, Relling Mary V. PubMed
  138. Polymorphisms in human MDR1 (P-glycoprotein): recent advances and clinical relevance. Clinical pharmacology and therapeutics. 2004. Marzolini Catia, Paus Erik, Buclin Thierry, Kim Richard B. PubMed
  139. Childhood and adolescent lymphoid and myeloid leukemia. Hematology / the Education Program of the American Society of Hematology. American Society of Hematology. Education Program. 2004. Pui Ching-Hon, Schrappe Martin, Ribeiro Raul C, Niemeyer Charlotte M. PubMed
  140. Can the genotoxicity of chemotherapy be predicted?. Lancet. 2004. Pui Ching-Hon, Relling Mary V. PubMed
  141. A resource to acquire and summarize pharmacogenetics knowledge in the literature. Studies in health technology and informatics. 2004. Rubin Daniel L, Carrillo Michelle, Woon Mark, Conroy John, Klein Teri E, Altman Russ B. PubMed
  142. Hepatic CYP2B6 expression: gender and ethnic differences and relationship to CYP2B6 genotype and CAR (constitutive androstane receptor) expression. The Journal of pharmacology and experimental therapeutics. 2003. Lamba Vishal, Lamba Jatinder, Yasuda Kazuto, Strom Stephen, Davila Julio, Hancock Michael L, Fackenthal James D, Rogan Peter K, Ring Barbara, Wrighton Steven A, Schuetz Erin G. PubMed
  143. PharmGKB: the pharmacogenetics and pharmacogenomics knowledge base. The pharmacogenomics journal. 2004. Klein T E, Altman R B. PubMed
  144. The Gly389Arg beta1-adrenergic receptor polymorphism: a predictor of response to beta-blocker treatment?. Clinical pharmacology and therapeutics. 2003. Brodde Otto-Erich, Stein C Michael. PubMed
  145. Homocysteine, pharmacogenetics, and neurotoxicity in children with leukemia. Journal of clinical oncology : official journal of the American Society of Clinical Oncology. 2003. Kishi Shinji, Griener James, Cheng Cheng, Das Soma, Cook Edwin H, Pei Deqing, Hudson Melissa, Rubnitz Jeffrey, Sandlund John T, Pui Ching-Hon, Relling Mary V. PubMed
  146. Large scale study of protein domain distribution in the context of alternative splicing. Nucleic acids research. 2003. Liu Shuo, Altman Russ B. PubMed
  147. The computational analysis of scientific literature to define and recognize gene expression clusters. Nucleic acids research. 2003. Raychaudhuri Soumya, Chang Jeffrey T, Imam Farhad, Altman Russ B. PubMed
  148. Characterization of multiple promoters in the human carboxylesterase 2 gene. Pharmacogenetics. 2003. Wu Michael H, Chen Peixian, Remo Benjamin F, Cook Edwin H, Das Soma, Dolan M Eileen. PubMed
  149. A Bayesian framework for combining heterogeneous data sources for gene function prediction (in Saccharomyces cerevisiae). Proceedings of the National Academy of Sciences of the United States of America. 2003. Troyanskaya Olga G, Dolinski Kara, Owen Art B, Altman Russ B, Botstein David. PubMed
  150. Variability of heart rate correction methods for the QT interval. British journal of clinical pharmacology. 2003. Desai Mehul, Li Lang, Desta Zeruesenay, Malik Marek, Flockhart David. PubMed
  151. A pharmacogenetic study of uridine diphosphate-glucuronosyltransferase 2B7 in patients receiving morphine. Clinical pharmacology and therapeutics. 2003. Sawyer Michael B, Innocenti Federico, Das Soma, Cheng Cheng, Ramírez Jacqueline, Pantle-Fisher Friedl H, Wright Constance, Badner Judith, Pei Deqing, Boyett James M, Cook Edwin, Ratain Mark J. PubMed
  152. Granulocyte colony-stimulating factor and the risk of secondary myeloid malignancy after etoposide treatment. Blood. 2003. Relling Mary V, Boyett James M, Blanco Javier G, Raimondi Susana, Behm Frederick G, Sandlund John T, Rivera Gaston K, Kun Larry E, Evans William E, Pui Ching-Hon. PubMed
  153. Genetic sequence data for pharmacogenomics. Current opinion in drug discovery & development. 2003. Altman Russ B. PubMed
  154. Irinotecan treatment in cancer patients with UGT1A1 polymorphisms. Oncology (Williston Park, N.Y.). 2003. Innocenti Federico, Ratain Mark J. PubMed
  155. The CYP3A4*1B variant is related to the onset of puberty, a known risk factor for the development of breast cancer. Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology. 2003. Kadlubar Fred F, Berkowitz Gertrud S, Delongchamp Robert R, Wang Charles, Green Bridgett L, Tang George, Lamba Jatinder, Schuetz Erin, Wolff Mary S. PubMed
  156. A common beta1-adrenergic receptor polymorphism (Arg389Gly) affects blood pressure response to beta-blockade. Clinical pharmacology and therapeutics. 2003. Sofowora G G, Dishy V, Muszkat M, Xie H G, Kim R B, Harris P A, Prasad H C, Byrne D W, Nair U B, Wood A J J, Stein C M. PubMed
  157. A functional analysis of disease-associated mutations in the androgen receptor gene. Nucleic acids research. 2003. Mooney Sean D, Klein Teri E, Altman Russ B, Trifiro Mark A, Gottlieb Bruce. PubMed
  158. Interethnic difference in the allelic distribution of human epidermal growth factor receptor intron 1 polymorphism. Clinical cancer research : an official journal of the American Association for Cancer Research. 2003. Liu Wanqing, Innocenti Federico, Chen Peixian, Das Soma, Cook Edwin H, Ratain Mark J. PubMed
  159. Privacy issues in personalized medicine. Pharmacogenomics. 2003. Vaszar Laszlo T, Cho Mildred K, Raffin Thomas A. PubMed
  160. A literature-based method for assessing the functional coherence of a gene group. Bioinformatics (Oxford, England). 2003. Raychaudhuri Soumya, Altman Russ B. PubMed
  161. Knowledge acquisition, consistency checking and concurrency control for Gene Ontology (GO). Bioinformatics (Oxford, England). 2003. Yeh Iwei, Karp Peter D, Noy Natalya F, Altman Russ B. PubMed
  162. Indexing pharmacogenetic knowledge on the World Wide Web. Pharmacogenetics. 2003. Altman Russ B, Flockhart David A, Sherry Stephen T, Oliver Diane E, Rubin Daniel L, Klein Teri E. PubMed
  163. Haplotype structure of the UDP-glucuronosyltransferase 1A1 promoter in different ethnic groups. Pharmacogenetics. 2002. Innocenti Federico, Grimsley Carrie, Das Soma, Ramírez Jacqueline, Cheng Cheng, Kuttab-Boulos Hala, Ratain Mark J, Di Rienzo Anna. PubMed
  164. A personalized and automated dbSNP surveillance system. Proceedings / IEEE Computer Society Bioinformatics Conference. IEEE Computer Society Bioinformatics Conference. 2003. Liu Shuo, Lin Steve, Woon Mark, Klein Teri E, Altman Russ B. PubMed
  165. Pharmacokinetics and QT interval pharmacodynamics of oral haloperidol in poor and extensive metabolizers of CYP2D6. The pharmacogenomics journal. 2003. Desai M, Tanus-Santos J E, Li L, Gorski J C, Arefayene M, Liu Y, Desta Z, Flockhart D A. PubMed
  166. CYP2C9 allelic variants: ethnic distribution and functional significance. Advanced drug delivery reviews. 2002. Xie Hong-Guang, Prasad Harish C, Kim Richard B, Stein C Michael. PubMed
  167. Nonparametric methods for identifying differentially expressed genes in microarray data. Bioinformatics (Oxford, England). 2002. Troyanskaya Olga G, Garber Mitchell E, Brown Patrick O, Botstein David, Altman Russ B. PubMed
  168. Genetic polymorphisms in CYP3A5, CYP3A4 and NQO1 in children who developed therapy-related myeloid malignancies. Pharmacogenetics. 2002. Blanco Javier G, Edick Mathew J, Hancock Michael L, Winick Naomi J, Dervieux Thierry, Amylon Michael D, Bash Robert O, Behm Frederick G, Camitta Bruce M, Pui Ching-Hon, Raimondi Susana C, Relling Mary V. PubMed
  169. Promises of text processing: natural language processing meets AI. Drug discovery today. 2002. Chang Jeffrey T, Altman Russ B. PubMed
  170. Using text analysis to identify functionally coherent gene groups. Genome research. 2002. Raychaudhuri Soumya, Schütze Hinrich, Altman Russ B. PubMed
  171. Determining the genomic locations of repetitive DNA sequences with a whole-genome microarray: IS6110 in Mycobacterium tuberculosis. Journal of clinical microbiology. 2002. Kivi Mårten, Liu Xuemin, Raychaudhuri Soumya, Altman Russ B, Small Peter M. PubMed
  172. In vitro characterization of hepatic flavopiridol metabolism using human liver microsomes and recombinant UGT enzymes. Pharmaceutical research. 2002. Ramírez Jacqueline, Iyer Lalitha, Journault Kim, Bélanger Patrick, Innocenti Federico, Ratain Mark J, Guillemette Chantal. PubMed
  173. Allelic variants in long-QT disease genes in patients with drug-associated torsades de pointes. Circulation. 2002. Yang Ping, Kanki Hideaki, Drolet Benoit, Yang Tao, Wei Jian, Viswanathan Prakash C, Hohnloser Stefan H, Shimizu Wataru, Schwartz Peter J, Stanton Marshall, Murray Katherine T, Norris Kris, George Alfred L, Roden Dan M. PubMed
  174. Common allelic variants of cytochrome P4503A4 and their prevalence in different populations. Pharmacogenetics. 2002. Lamba Jatinder K, Lin Yvonne S, Thummel Kenneth, Daly Ann, Watkins Paul B, Strom Stephen, Zhang Jiong, Schuetz Erin G. PubMed
  175. Associating genes with gene ontology codes using a maximum entropy analysis of biomedical literature. Genome research. 2002. Raychaudhuri Soumya, Chang Jeffrey T, Sutphin Patrick D, Altman Russ B. PubMed
  176. PharmGKB: the Pharmacogenetics Knowledge Base. Nucleic acids research. 2002. Hewett Micheal, Oliver Diane E, Rubin Daniel L, Easton Katrina L, Stuart Joshua M, Altman Russ B, Klein Teri E. PubMed
  177. Challenges for biomedical informatics and pharmacogenomics. Annual review of pharmacology and toxicology. 2002. Altman Russ B, Klein Teri E. PubMed
  178. Representing genetic sequence data for pharmacogenomics: an evolutionary approach using ontological and relational models. Bioinformatics (Oxford, England). 2002. Rubin Daniel L, Shafa Farhad, Oliver Diane E, Hewett Micheal, Altman Russ B. PubMed
  179. Creating an online dictionary of abbreviations from MEDLINE. Journal of the American Medical Informatics Association : JAMIA. 2002. Chang Jeffrey T, Schütze Hinrich, Altman Russ B. PubMed
  180. Automating data acquisition into ontologies from pharmacogenetics relational data sources using declarative object definitions and XML. Pacific Symposium on Biocomputing. Pacific Symposium on Biocomputing. 2002. Rubin Daniel L, Hewett Micheal, Oliver Diane E, Klein Teri E, Altman Russ B. PubMed
  181. Ontology development for a pharmacogenetics knowledge base. Pacific Symposium on Biocomputing. Pacific Symposium on Biocomputing. 2002. Oliver Diane E, Rubin Daniel L, Stuart Joshua M, Hewett Micheal, Klein Teri E, Altman Russ B. PubMed
  182. The human pregnane X receptor: genomic structure and identification and functional characterization of natural allelic variants. Pharmacogenetics. 2001. Zhang J, Kuehl P, Green E D, Touchman J W, Watkins P B, Daly A, Hall S D, Maurel P, Relling M, Brimer C, Yasuda K, Wrighton S A, Hancock M, Kim R B, Strom S, Thummel K, Russell C G, Hudson J R, Schuetz E G, Boguski M S. PubMed
  183. Missing value estimation methods for DNA microarrays. Bioinformatics (Oxford, England). 2001. Troyanskaya O, Cantor M, Sherlock G, Brown P, Hastie T, Tibshirani R, Botstein D, Altman R B. PubMed
  184. International Childhood Acute Lymphoblastic Leukemia Workshop: Sausalito, CA, 30 November-1 December 2000. Leukemia : official journal of the Leukemia Society of America, Leukemia Research Fund, U.K. 2001. Pui C H, Sallan S, Relling M V, Masera G, Evans W E. PubMed
  185. Basic microarray analysis: grouping and feature reduction. Trends in biotechnology. 2001. Raychaudhuri S, Sutphin P D, Chang J T, Altman R B. PubMed
  186. Sequence diversity in CYP3A promoters and characterization of the genetic basis of polymorphic CYP3A5 expression. Nature genetics. 2001. Kuehl P, Zhang J, Lin Y, Lamba J, Assem M, Schuetz J, Watkins P B, Daly A, Wrighton S A, Hall S D, Maurel P, Relling M, Brimer C, Yasuda K, Venkataramanan R, Strom S, Thummel K, Boguski M S, Schuetz E. PubMed
  187. Including biological literature improves homology search. Pacific Symposium on Biocomputing. Pacific Symposium on Biocomputing. 2001. Chang J T, Raychaudhuri S, Altman R B. PubMed
  188. ViewFeature: integrated feature analysis and visualization. Pacific Symposium on Biocomputing. Pacific Symposium on Biocomputing. 2001. Banatao D R, Huang C C, Babbitt P C, Altman R B, Klein T E. PubMed
  189. Integrating genotype and phenotype information: an overview of the PharmGKB project. Pharmacogenetics Research Network and Knowledge Base. The pharmacogenomics journal. 2001. Klein T E, Chang J T, Cho M K, Easton K L, Fergerson R, Hewett M, Lin Z, Liu Y, Liu S, Oliver D E, Rubin D L, Shafa F, Stuart J M, Altman R B. PubMed
  190. The interactions between clinical informatics and bioinformatics: a case study. Journal of the American Medical Informatics Association : JAMIA. 2000. Altman R B. PubMed
  191. Biomedical computation at Stanford University: a larger umbrella for the future. M.D. computing : computers in medical practice. 2000. Altman R B. PubMed