Drug Labels

PharmGKB annotates drug labels containing pharmacogenetic information approved by the US Food and Drug Administration (FDA), European Medicines Agency (EMA), the Pharmaceuticals and Medical Devices Agency, Japan (PMDA), and Health Canada (Santé Canada) (HCSC). PharmGKB annotations provide a brief summary of the PGx in the label, an excerpt from the label and a downloadable highlighted label PDF file. A list of genes and phenotypes found within the label is mapped to label section headers and listed at the end of each annotation. PharmGKB also attempts to interpret the level of action implied in each label with the "PGx Level" tag.

See the legend for more information about drug label sources and PGx Levels.

We welcome any information regarding drug labels containing PGx information approved by the FDA, EMA, PMDA, HCSC or other Medicine Agencies around the world - please contact feedback.


Drug FDA EMA PMDA HCSC
abacavir B
abiraterone
acetaminophen
afatinib B
afutuzumab B
alectinib B
alirocumab B
aliskiren
amitriptyline B
anastrozole B
arformoterol B
aripiprazole B
Actionable PGx
has dosing information
arsenic trioxide B
atazanavir
atomoxetine B
Actionable PGx
has dosing information
atorvastatin
axitinib
azathioprine B
belimumab
belinostat B
Actionable PGx
has dosing information
blinatumomab B
boceprevir B
bosutinib B
brentuximab vedotin
brexpiprazole B
Actionable PGx
has dosing information
brivaracetam
Actionable PGx
has dosing information
busulfan B
cabazitaxel
cabozantinib B
capecitabine B
carbamazepine B
carglumic acid B
carisoprodol B
carvedilol B
celecoxib B
Actionable PGx
has dosing information
ceritinib B
cetuximab B
cevimeline B
chloroquine B
chlorpropamide B
cholic acid B
cisplatin B
citalopram B
Actionable PGx
has dosing information
clobazam B
Actionable PGx
has dosing information
clomifene
clomipramine B
clopidogrel B
clozapine B
cobimetinib B
codeine B
crizotinib B
dabrafenib B
dapsone B
darifenacin
darunavir
dasatinib B
denileukin diftitox B
desflurane
desipramine B
desloratadine
dexlansoprazole B
dextromethorphan B
diazepam B
dinutuximab B
divalproex sodium
dolutegravir B
doxepin B
dronedarone
drospirenone B
efavirenz
eliglustat B
Genetic testing required
has dosing information
elosulfase alfa B
eltrombopag B
emtricitabine
erlotinib B
erythromycin
escitalopram B
esomeprazole B
ethinyl estradiol B
everolimus B
evolocumab B
exemestane B
fampridine
fesoterodine
flibanserin
fluorouracil B
fluoxetine B
flurbiprofen B
fluvoxamine B
fosamprenavir
fulvestrant B
galantamine B
gefitinib B
glibenclamide B
glimepiride B
glipizide B
homoharringtonine B
hydralazine B
ibritumomab
ibrutinib B
iloperidone B
Actionable PGx
has dosing information
imatinib B
imipramine B
indacaterol B
indinavir
irinotecan B
Actionable PGx
has dosing information
isoflurane
isoniazid B
isosorbide dinitrate B
ivabradine
ivacaftor B
ivacaftor / lumacaftor B
lacosamide B
lansoprazole B
lapatinib B
lenalidomide B
lesinurad B
letrozole B
lidocaine B
lomitapide B
mafenide B
maraviroc
mercaptopurine B
methylene blue B
metoclopramide B
metoprolol B
mipomersen B
modafinil B
mycophenolic acid B
nalidixic acid B
nefazodone B
nelfinavir
nilotinib B
nitrofurantoin B
nivolumab B
norelgestromin
norfloxacin
nortriptyline B
ofatumumab
olanzapine
olaparib B
omeprazole B
osimertinib
oxcarbazepine
palbociclib B
palonosetron B
panitumumab B
pantoprazole B
Parathyroid Hormones And Analogues B
paroxetine B
pazopanib B
peginterferon alfa-2b
pegloticase B
pembrolizumab B
perphenazine B
pertuzumab B
phenylacetic acid B
phenytoin B
pimozide B
Genetic testing required
has dosing information
ponatinib B
posaconazole
prasugrel B
pravastatin B
prilocaine B
primaquine B
probenecid
propafenone B
propranolol B
protriptyline B
pyrazinamide B
quinidine B
quinine B
rabeprazole B
ranolazine
rasburicase B
regorafenib
rifampin B
risperidone B
ritonavir
rituximab B
rosuvastatin B
ruxolitinib
sevoflurane B
sildenafil
simeprevir B
sirolimus
sodium benzoate B
sodium nitrite B
sodium phenylbutyrate
sofosbuvir B
succimer B
succinylcholine
sulfadiazine
sulfamethoxazole B
sulfasalazine
sulfisoxazole
sunitinib
tamoxifen B
telaprevir B
telithromycin
tenofovir
terbinafine
tetrabenazine B
Genetic testing required
has dosing information
thioguanine B
thioridazine B
ticagrelor B
timolol
tiotropium
tipranavir
tolterodine B
tositumomab B
tramadol B
trametinib B
trastuzumab B
trastuzumab emtansine B
tretinoin B
trimethoprim B
trimipramine B
valproic acid B
vandetanib
vardenafil
velaglucerase alfa
vemurafenib B
venlafaxine B
viekira pak B
vitamin c B
voriconazole B
vortioxetine B
Actionable PGx
has dosing information
warfarin B
Actionable PGx
has dosing information
zonisamide

Last modified on Wed Sep 14 11:05:03 PDT 2016 (PMDA Label for tolterodine and CYP2D6)