Prevention of depression with escitalopram in patients undergoing treatment for head and neck cancer: randomized, double-blind, placebo-controlled clinical trial
Lydiatt William M,
Schmid Kendra K,
Burke William J
JAMA otolaryngology-- head & neck surgery (2013).
Major depressive disorder develops in up to half the patients undergoing treatment for head and neck cancer, resulting in significant morbidity; therefore, preventing depression during cancer treatment may be of great benefit.