Genome-wide association identifies the T gene as a novel asthma pharmacogenetic locus by Tantisira Kelan G, Damask Amy, Szefler Stanley J, Schuemann Brooke, Markezich Amy, Su Jessica, Klanderman Barbara, Sylvia Jody, Wu Rongling, Martinez Fernando, Boushey Homer A, Chinchilli Vernon M, Mauger Dave, Weiss Scott T, Israel Elliot, SHARP Investigators in American journal of respiratory and critical care medicine (2012). PubMed


To date, most studies aimed at discovering genetic factors influencing treatment response in asthma have focused on biologic candidate genes. Genome-wide association studies (GWAS) can rapidly identify novel pharmacogenetic loci.

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