Genome-wide association identifies the T gene as a novel asthma pharmacogenetic locus
Tantisira Kelan G,
Szefler Stanley J,
Boushey Homer A,
Chinchilli Vernon M,
Weiss Scott T,
American journal of respiratory and critical care medicine (2012).
To date, most studies aimed at discovering genetic factors influencing treatment response in asthma have focused on biologic candidate genes. Genome-wide association studies (GWAS) can rapidly identify novel pharmacogenetic loci.