ARID5B genetic polymorphisms contribute to racial disparities in the incidence and treatment outcome of childhood acute lymphoblastic leukemia by Xu Heng, Cheng Cheng, Devidas Meenakshi, Pei Deqing, Fan Yiping, Yang Wenjian, Neale Geoff, Scheet Paul, Burchard Esteban G, Torgerson Dara G, Eng Celeste, Dean Michael, Antillon Frederico, Winick Naomi J, Martin Paul L, Willman Cheryl L, Camitta Bruce M, Reaman Gregory H, Carroll William L, Loh Mignon, Evans William E, Pui Ching-Hon, Hunger Stephen P, Relling Mary V, Yang Jun J in Journal of clinical oncology : official journal of the American Society of Clinical Oncology (2012).

[PMID: 22291082] PubMed


Recent genome-wide screens have identified genetic variations in ARID5B associated with susceptibility to childhood acute lymphoblastic leukemia (ALL). We sought to determine the contribution of ARID5B single nucleotide polymorphisms (SNPs) to racial disparities in ALL susceptibility and treatment outcome.

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