Characterization of genetic variation and natural selection at the arylamine N-acetyltransferase genes in global human populations
Mortensen Holly M,
Nyambo Thomas B,
Omar Sabah A,
Tishkoff Sarah A
Functional variability at the arylamine N-acetyltransferase genes is associated with drug response in humans and may have been adaptive in the past owing to selection pressure from diet and exposure to toxins during human evolution.