PharmGKB summary: methotrexate pathway by Mikkelsen Torben S, Thorn Caroline F, Yang Jun J, Ulrich Cornelia M, French Deborah, Zaza Gianluigi, Dunnenberger Henry M, Marsh Sharon, McLeod Howard L, Giacomini Kathy, Becker Mara L, Gaedigk Roger, Leeder James Steven, Kager Leo, Relling Mary V, Evans William, Klein Teri E, Altman Russ B in Pharmacogenetics and genomics (2011).

[PMID: 21317831] PubMed


Discussed In Paper


Rx Annotations

No dosing information annotated.


  1. Representation of transport and exchange of methotrexate in the brain.

  2. Methotrexate cellular disposition and effects.

  3. Diagramatic representation of uptake, transport and elimination of methotrexate.