Selective serotonin reuptake inhibitors and breast cancer mortality in women receiving tamoxifen: a population based cohort study by Kelly Catherine M, Juurlink David N, Gomes Tara, Duong-Hua Minh, Pritchard Kathleen I, Austin Peter C, Paszat Lawrence F in BMJ (Clinical research ed.) (2010).

[PMID: 20142325] PubMed


To characterise whether some selective serotonin reuptake inhibitor (SSRI) antidepressants reduce tamoxifen's effectiveness by inhibiting its bioactivation by cytochrome P450 2D6 (CYP2D6).

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