Effect of aspirin or resistant starch on colorectal neoplasia in the Lynch syndrome by Burn John, Bishop D Timothy, Mecklin Jukka-Pekka, Macrae Finlay, Möslein Gabriela, Olschwang Sylviane, Bisgaard Marie-Luise, Ramesar Raj, Eccles Diana, Maher Eamonn R, Bertario Lucio, Jarvinen Heikki J, Lindblom Annika, Evans D Gareth, Lubinski Jan, Morrison Patrick J, Ho Judy W C, Vasen Hans F A, Side Lucy, Thomas Huw J W, Scott Rodney J, Dunlop Malcolm, Barker Gail, Elliott Faye, Jass Jeremy R, Fodde Ricardo, Lynch Henry T, Mathers John C, CAPP2 Investigators in The New England journal of medicine (2008). PubMed


Observational and epidemiologic data indicate that the use of aspirin reduces the risk of colorectal neoplasia; however, the effects of aspirin in the Lynch syndrome (hereditary nonpolyposis colon cancer) are not known. Resistant starch has been associated with an antineoplastic effect on the colon.

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