Effect of aspirin or resistant starch on colorectal neoplasia in the Lynch syndrome by Burn John, Bishop D Timothy, Mecklin Jukka-Pekka, Macrae Finlay, Möslein Gabriela, Olschwang Sylviane, Bisgaard Marie-Luise, Ramesar Raj, Eccles Diana, Maher Eamonn R, Bertario Lucio, Jarvinen Heikki J, Lindblom Annika, Evans D Gareth, Lubinski Jan, Morrison Patrick J, Ho Judy W C, Vasen Hans F A, Side Lucy, Thomas Huw J W, Scott Rodney J, Dunlop Malcolm, Barker Gail, Elliott Faye, Jass Jeremy R, Fodde Ricardo, Lynch Henry T, Mathers John C, CAPP2 Investigators in The New England journal of medicine (2008).

[PMID: 19073976] PubMed

Abstract

Observational and epidemiologic data indicate that the use of aspirin reduces the risk of colorectal neoplasia; however, the effects of aspirin in the Lynch syndrome (hereditary nonpolyposis colon cancer) are not known. Resistant starch has been associated with an antineoplastic effect on the colon.

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