Bitter taste receptor gene polymorphisms are an important factor in the development of nicotine dependence in African Americans by Mangold J E, Payne T J, Ma J Z, Chen G, Li M D in Journal of medical genetics (2008).

[PMID: 18524836] PubMed

Abstract

Bitter sensitivity varies among individuals and ethnic groups partly due to polymorphisms in taste receptor genes (TAS2Rs). Although previous psychophysical studies suggest that taste status plays a role in nicotine dependence (ND), genetic evidence is lacking.

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