Bitter taste receptor gene polymorphisms are an important factor in the development of nicotine dependence in African Americans by Mangold J E, Payne T J, Ma J Z, Chen G, Li M D in Journal of medical genetics (2008). PubMed


Bitter sensitivity varies among individuals and ethnic groups partly due to polymorphisms in taste receptor genes (TAS2Rs). Although previous psychophysical studies suggest that taste status plays a role in nicotine dependence (ND), genetic evidence is lacking.

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