Vasopressin versus norepinephrine infusion in patients with septic shock by Russell James A, Walley Keith R, Singer Joel, Gordon Anthony C, H├ębert Paul C, Cooper D James, Holmes Cheryl L, Mehta Sangeeta, Granton John T, Storms Michelle M, Cook Deborah J, Presneill Jeffrey J, Ayers Dieter, VASST Investigators in The New England journal of medicine (2008).

[PMID: 18305265] PubMed


Vasopressin is commonly used as an adjunct to catecholamines to support blood pressure in refractory septic shock, but its effect on mortality is unknown. We hypothesized that low-dose vasopressin as compared with norepinephrine would decrease mortality among patients with septic shock who were being treated with conventional (catecholamine) vasopressors.

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