Hydrocortisone therapy for patients with septic shock by Sprung Charles L, Annane Djillali, Keh Didier, Moreno Rui, Singer Mervyn, Freivogel Klaus, Weiss Yoram G, Benbenishty Julie, Kalenka Armin, Forst Helmuth, Laterre Pierre-Francois, Reinhart Konrad, Cuthbertson Brian H, Payen Didier, Briegel Josef, CORTICUS Study Group in The New England journal of medicine (2008).

[PMID: 18184957] PubMed


Hydrocortisone is widely used in patients with septic shock even though a survival benefit has been reported only in patients who remained hypotensive after fluid and vasopressor resuscitation and whose plasma cortisol levels did not rise appropriately after the administration of corticotropin.

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