Effect of anastrozole and tamoxifen as adjuvant treatment for early-stage breast cancer: 100-month analysis of the ATAC trial by Arimidex, Tamoxifen, Alone or in Combination (ATAC) Trialists' Group, Forbes John F, Cuzick Jack, Buzdar Aman, Howell Anthony, Tobias Jeffrey S, Baum Michael in The lancet oncology (2008).

[PMID: 18083636] PubMed


Little data exist on whether efficacy benefits or side-effects persist after 5 years of adjuvant treatment with an aromatase inhibitor. We aimed to study long-term outcomes in the Arimidex, Tamoxifen, Alone or in Combination (ATAC) trial that compares anastrozole with tamoxifen after a median follow-up of 100 months.

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