Low physical activity accentuates the effect of the FTO rs9939609 polymorphism on body fat accumulation by Andreasen Camilla H, Stender-Petersen Kirstine L, Mogensen Mette S, Torekov Signe S, Wegner Lise, Andersen Gitte, Nielsen Arne L, Albrechtsen Anders, Borch-Johnsen Knut, Rasmussen Signe S, Clausen Jesper O, Sandbaek Annelli, Lauritzen Torsten, Hansen Lars, Jørgensen Torben, Pedersen Oluf, Hansen Torben in Diabetes (2008). PubMed


Three independent studies have shown that variation in the fat mass and obesity-associated (FTO) gene associates with BMI and obesity. In the present study, the effect of FTO variation on metabolic traits including obesity, type 2 diabetes, and related quantitative phenotypes was examined.

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