Low physical activity accentuates the effect of the FTO rs9939609 polymorphism on body fat accumulation by Andreasen Camilla H, Stender-Petersen Kirstine L, Mogensen Mette S, Torekov Signe S, Wegner Lise, Andersen Gitte, Nielsen Arne L, Albrechtsen Anders, Borch-Johnsen Knut, Rasmussen Signe S, Clausen Jesper O, Sandbaek Annelli, Lauritzen Torsten, Hansen Lars, Jørgensen Torben, Pedersen Oluf, Hansen Torben in Diabetes (2008).

[PMID: 17942823] PubMed


Three independent studies have shown that variation in the fat mass and obesity-associated (FTO) gene associates with BMI and obesity. In the present study, the effect of FTO variation on metabolic traits including obesity, type 2 diabetes, and related quantitative phenotypes was examined.

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