A genetic risk factor for periodic limb movements in sleep by Stefansson Hreinn, Rye David B, Hicks Andrew, Petursson Hjorvar, Ingason Andres, Thorgeirsson Thorgeir E, Palsson Stefan, Sigmundsson Thordur, Sigurdsson Albert P, Eiriksdottir Ingibjorg, Soebech Emilia, Bliwise Donald, Beck Joseph M, Rosen Ami, Waddy Salina, Trotti Lynn M, Iranzo Alex, Thambisetty Madhav, Hardarson Gudmundur A, Kristjansson Kristleifur, Gudmundsson Larus J, Thorsteinsdottir Unnur, Kong Augustine, Gulcher Jeffrey R, Gudbjartsson Daniel, Stefansson Kari in The New England journal of medicine (2007).

[PMID: 17634447] PubMed


The restless legs syndrome (RLS) is a common neurologic disorder characterized by an irresistible urge to move the legs. It is a major cause of sleep disruption. Periodic limb movements in sleep are detectable in most patients with RLS and represent an objective physiological metric.

[ hide abstract ]

Discussed In Paper


Rx Annotations

No dosing information annotated.