The Alexander disease-causing glial fibrillary acidic protein mutant, R416W, accumulates into Rosenthal fibers by a pathway that involves filament aggregation and the association of alpha B-crystallin and HSP27 by Der Perng Ming, Su Mu, Wen Shu Fang, Li Rong, Gibbon Terry, Prescott Alan R, Brenner Michael, Quinlan Roy A in American journal of human genetics (2006).

[PMID: 16826512] PubMed

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