Gene:
DCXR
dicarbonyl/L-xylulose reductase

PharmGKB contains no dosing guidelines for this . To report known genotype-based dosing guidelines, or if you are interested in developing guidelines, click here.

PharmGKB has no annotated drug labels with pharmacogenomic information for this . If you know of a drug label with PGx, send us a message.

PharmGKB contains no Clinical Variants that meet the highest level of criteria.

Disclaimer: The PharmGKB's clinical annotations reflect expert consensus based on clinical evidence and peer-reviewed literature available at the time they are written and are intended only to assist clinicians in decision-making and to identify questions for further research. New evidence may have emerged since the time an annotation was submitted to the PharmGKB. The annotations are limited in scope and are not applicable to interventions or diseases that are not specifically identified.

The annotations do not account for individual variations among patients, and cannot be considered inclusive of all proper methods of care or exclusive of other treatments. It remains the responsibility of the health-care provider to determine the best course of treatment for a patient. Adherence to any guideline is voluntary, with the ultimate determination regarding its application to be made solely by the clinician and the patient. PharmGKB assumes no responsibility for any injury or damage to persons or property arising out of or related to any use of the PharmGKB clinical annotations, or for any errors or omissions.

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Overview

Alternate Names:  short chain dehydrogenase/reductase family 20C, member 1
Alternate Symbols:  DCR; KIDCR; SDR20C1
PharmGKB Accession Id: PA38772

Details

Cytogenetic Location: chr17 : q25.3 - q25.3
GP mRNA Boundary: chr17 : 79993757 - 79995573
GP Gene Boundary: chr17 : 79990757 - 80005573
Strand: minus

Visualization

UCSC has a Genome Browser that you can use to view PharmGKB annotations for this gene in context with many other sources of information.

View on UCSC Browser
The mRNA boundaries are calculated using the gene's default feature set from NCBI, mapped onto the UCSC Golden Path. PharmGKB sets gene boundaries by expanding the mRNA boundaries by no less than 10,000 bases upstream (5') and 3,000 bases downstream (3') to allow for potential regulatory regions.

LinkOuts

NCBI Gene:
51181
OMIM:
260800
608347
UCSC Genome Browser:
NM_016286
RefSeq RNA:
NM_001195218
NM_016286
RefSeq Protein:
NP_001182147
NP_057370
RefSeq DNA:
NT_010663
UniProtKB:
DCXR_HUMAN (Q7Z4W1)
Ensembl:
ENSG00000169738
GenAtlas:
DCXR
GeneCard:
DCXR
MutDB:
DCXR
ALFRED:
LO250804T
HuGE:
DCXR
Comparative Toxicogenomics Database:
51181
ModBase:
Q7Z4W1
HumanCyc Gene:
HS09999
HGNC:
18985

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