Gene:
USP2
ubiquitin specific peptidase 2

PharmGKB contains no dosing guidelines for this . To report known genotype-based dosing guidelines, or if you are interested in developing guidelines, click here.

PharmGKB has no annotated drug labels with pharmacogenomic information for this . If you know of a drug label with PGx, send us a message.

PharmGKB contains no Clinical Variants that meet the highest level of criteria.

Disclaimer: The PharmGKB's clinical annotations reflect expert consensus based on clinical evidence and peer-reviewed literature available at the time they are written and are intended only to assist clinicians in decision-making and to identify questions for further research. New evidence may have emerged since the time an annotation was submitted to the PharmGKB. The annotations are limited in scope and are not applicable to interventions or diseases that are not specifically identified.

The annotations do not account for individual variations among patients, and cannot be considered inclusive of all proper methods of care or exclusive of other treatments. It remains the responsibility of the health-care provider to determine the best course of treatment for a patient. Adherence to any guideline is voluntary, with the ultimate determination regarding its application to be made solely by the clinician and the patient. PharmGKB assumes no responsibility for any injury or damage to persons or property arising out of or related to any use of the PharmGKB clinical annotations, or for any errors or omissions.

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Overview

Alternate Names:  None
Alternate Symbols:  UBP41
PharmGKB Accession Id: PA37244

Details

Cytogenetic Location: chr11 : q23.3 - q23.3
GP mRNA Boundary: chr11 : 119225925 - 119252436
GP Gene Boundary: chr11 : 119222925 - 119262436
Strand: minus

Visualization

UCSC has a Genome Browser that you can use to view PharmGKB annotations for this gene in context with many other sources of information.

View on UCSC Browser
The mRNA boundaries are calculated using the gene's default feature set from NCBI, mapped onto the UCSC Golden Path. PharmGKB sets gene boundaries by expanding the mRNA boundaries by no less than 10,000 bases upstream (5') and 3,000 bases downstream (3') to allow for potential regulatory regions.

LinkOuts

NCBI Gene:
9099
OMIM:
604725
UCSC Genome Browser:
NM_004205
RefSeq RNA:
NM_004205
NM_171997
RefSeq Protein:
NP_004196
NP_741994
RefSeq DNA:
NT_033899
UniProtKB:
UBP2_HUMAN (O75604)
Ensembl:
ENSG00000036672
GenAtlas:
USP2
GeneCard:
USP2
MutDB:
USP2
ALFRED:
LO046831W
HuGE:
USP2
Comparative Toxicogenomics Database:
9099
ModBase:
O75604
HumanCyc Gene:
HS00519
HGNC:
12618

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