Gene:
NCBP2
nuclear cap binding protein subunit 2, 20kDa

PharmGKB contains no prescribing info for this . Contact us to report known genotype-based dosing guidelines, or if you are interested in developing guidelines.

PharmGKB has no annotated drug labels with pharmacogenomic information for this . If you know of a drug label with PGx, send us a message.

PharmGKB contains no Clinical Variants that meet the highest level of criteria.

Disclaimer: The PharmGKB's clinical annotations reflect expert consensus based on clinical evidence and peer-reviewed literature available at the time they are written and are intended only to assist clinicians in decision-making and to identify questions for further research. New evidence may have emerged since the time an annotation was submitted to the PharmGKB. The annotations are limited in scope and are not applicable to interventions or diseases that are not specifically identified.

The annotations do not account for individual variations among patients, and cannot be considered inclusive of all proper methods of care or exclusive of other treatments. It remains the responsibility of the health-care provider to determine the best course of treatment for a patient. Adherence to any guideline is voluntary, with the ultimate determination regarding its application to be made solely by the clinician and the patient. PharmGKB assumes no responsibility for any injury or damage to persons or property arising out of or related to any use of the PharmGKB clinical annotations, or for any errors or omissions.

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Overview

Alternate Names:  None
Alternate Symbols:  CBP20; Cbc2; NIP1
PharmGKB Accession Id: PA31462

Details

Cytogenetic Location: chr3 : q29 - q29
GP mRNA Boundary: chr3 : 196662273 - 196669464
GP Gene Boundary: chr3 : 196659273 - 196679464
Strand: minus

Visualization

UCSC has a Genome Browser that you can use to view PharmGKB annotations for this gene in context with many other sources of information.

View on UCSC Browser
The mRNA boundaries are calculated using the gene's default feature set from NCBI, mapped onto the UCSC Golden Path. PharmGKB sets gene boundaries by expanding the mRNA boundaries by no less than 10,000 bases upstream (5') and 3,000 bases downstream (3') to allow for potential regulatory regions.

Publications related to NCBP2: 1

No Dosing Guideline available No Drug Label available No Clinical Annotation available No Variant Annotation available No VIP available No VIP available
Classification, subtype discovery, and prediction of outcome in pediatric acute lymphoblastic leukemia by gene expression profiling. Cancer cell. 2002. Yeoh Eng-Juh, et al. PubMed

LinkOuts

NCBI Gene:
22916
OMIM:
605133
UCSC Genome Browser:
NM_007362
RefSeq RNA:
NM_001042540
NM_007362
RefSeq Protein:
NP_001036005
NP_031388
RefSeq DNA:
NT_029928
UniProtKB:
NCBP2_HUMAN (P52298)
Ensembl:
ENSG00000114503
GenAtlas:
NCBP2
GeneCard:
NCBP2
MutDB:
NCBP2
ALFRED:
LO248515Z
HuGE:
NCBP2
Comparative Toxicogenomics Database:
22916
ModBase:
P52298
HumanCyc Gene:
HS03775
HGNC:
7659

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