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PharmGKB contains no Clinical Variants that meet the highest level of criteria.
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The annotations do not account for individual variations among patients, and cannot be considered inclusive of all proper methods of care or exclusive of other treatments. It remains the responsibility of the health-care provider to determine the best course of treatment for a patient. Adherence to any guideline is voluntary, with the ultimate determination regarding its application to be made solely by the clinician and the patient. PharmGKB assumes no responsibility for any injury or damage to persons or property arising out of or related to any use of the PharmGKB clinical annotations, or for any errors or omissions.
|Alternate Names:||cardiomyopathy, hypertrophic 1|
|Alternate Symbols: ||None|
|PharmGKB Accession Id:||PA31373|
|Cytogenetic Location:||chr14 : q12 - q11.2|
|GP mRNA Boundary†:||chr14 : 23851199 - 23877486|
|GP Gene Boundary†:||chr14 : 23848199 - 23887486|
Publications related to MYH6: 2
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- DG Dosing Guideline information is available
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||A rare variant in MYH6 is associated with high risk of sick sinus syndrome. Nature genetics. 2011. Holm Hilma, et al.|
||Control of stress-dependent cardiac growth and gene expression by a microRNA. Science (New York, N.Y.). 2007. van Rooij Eva, et al.|