Gene:
MCAM
melanoma cell adhesion molecule

PharmGKB contains no dosing guidelines for this . To report known genotype-based dosing guidelines, or if you are interested in developing guidelines, click here.

PharmGKB has no annotated drug labels with pharmacogenomic information for this . If you know of a drug label with PGx, send us a message.

PharmGKB contains no Clinical Variants that meet the highest level of criteria.

Disclaimer: The PharmGKB's clinical annotations reflect expert consensus based on clinical evidence and peer-reviewed literature available at the time they are written and are intended only to assist clinicians in decision-making and to identify questions for further research. New evidence may have emerged since the time an annotation was submitted to the PharmGKB. The annotations are limited in scope and are not applicable to interventions or diseases that are not specifically identified.

The annotations do not account for individual variations among patients, and cannot be considered inclusive of all proper methods of care or exclusive of other treatments. It remains the responsibility of the health-care provider to determine the best course of treatment for a patient. Adherence to any guideline is voluntary, with the ultimate determination regarding its application to be made solely by the clinician and the patient. PharmGKB assumes no responsibility for any injury or damage to persons or property arising out of or related to any use of the PharmGKB clinical annotations, or for any errors or omissions.

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Overview

Alternate Names:  Gicerin
Alternate Symbols:  CD146; MUC18
PharmGKB Accession Id: PA30678

Details

Cytogenetic Location: chr11 : q23.3 - q23.3
GP mRNA Boundary: chr11 : 119179234 - 119187840
GP Gene Boundary: chr11 : 119176234 - 119197840
Strand: minus
The mRNA boundaries are calculated using the gene's default feature set from NCBI, mapped onto the UCSC Golden Path. PharmGKB sets gene boundaries by expanding the mRNA boundaries by no less than 10,000 bases upstream (5') and 3,000 bases downstream (3') to allow for potential regulatory regions.

LinkOuts

Entrez Gene:
4162
OMIM:
155735
UCSC Genome Browser:
NM_006500
RefSeq RNA:
NM_006500
RefSeq Protein:
NP_006491
RefSeq DNA:
AC_000054
AC_000143
NC_000011
NT_033899
NW_001838042
NW_925173
UniProtKB:
MUC18_HUMAN (P43121)
Ensembl:
ENSG00000076706
GenAtlas:
MCAM
GeneCard:
MCAM
MutDB:
MCAM
ALFRED:
LO061055R
HuGE:
MCAM
Comparative Toxicogenomics Database:
4162
ModBase:
P43121
HumanCyc Gene:
HS01217
HGNC:
6934

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