Gene:
CADM1
cell adhesion molecule 1

PharmGKB contains no dosing guidelines for this . To report known genotype-based dosing guidelines, or if you are interested in developing guidelines, click here.

PharmGKB has no annotated drug labels with pharmacogenomic information for this . If you know of a drug label with PGx, send us a message.

PharmGKB contains no Clinical Variants that meet the highest level of criteria.

Disclaimer: The PharmGKB's clinical annotations reflect expert consensus based on clinical evidence and peer-reviewed literature available at the time they are written and are intended only to assist clinicians in decision-making and to identify questions for further research. New evidence may have emerged since the time an annotation was submitted to the PharmGKB. The annotations are limited in scope and are not applicable to interventions or diseases that are not specifically identified.

The annotations do not account for individual variations among patients, and cannot be considered inclusive of all proper methods of care or exclusive of other treatments. It remains the responsibility of the health-care provider to determine the best course of treatment for a patient. Adherence to any guideline is voluntary, with the ultimate determination regarding its application to be made solely by the clinician and the patient. PharmGKB assumes no responsibility for any injury or damage to persons or property arising out of or related to any use of the PharmGKB clinical annotations, or for any errors or omissions.

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Overview

Alternate Names:  IGSF4; TSLC1; nectin-like 2
Alternate Symbols:  BL2; IGSF4A; NECL2; Necl-2; RA175; ST17; SYNCAM; SYNCAM1
PharmGKB Accession Id: PA29764

Details

Cytogenetic Location: chr11 : q23.3 - q23.3
GP mRNA Boundary: chr11 : 115039933 - 115375241
GP Gene Boundary: chr11 : 115036933 - 115385241
Strand: minus

Visualization

UCSC has a Genome Browser that you can use to view PharmGKB annotations for this gene in context with many other sources of information.

View on UCSC Browser
The mRNA boundaries are calculated using the gene's default feature set from NCBI, mapped onto the UCSC Golden Path. PharmGKB sets gene boundaries by expanding the mRNA boundaries by no less than 10,000 bases upstream (5') and 3,000 bases downstream (3') to allow for potential regulatory regions.

PharmGKB Curated Pathways

Pathways created internally by PharmGKB based primarily on literature evidence.

PharmGKB contains no curated pathways for this gene. If you would like to volunteer to work on a pathway, please let us know.

External Pathways

Links to non-PharmGKB pathways.

  1. rac1 cell motility signaling pathway - (BioCarta via Pathway Interaction Database)
No related genes are available

Curated Information ?

Publications related to CADM1: 1

No Dosing Guideline available No Drug Label available No Clinical Annotation available No Variant Annotation available No VIP available No VIP available
Classification of pediatric acute lymphoblastic leukemia by gene expression profiling. Blood. 2003. Ross Mary E, et al. PubMed

LinkOuts

NCBI Gene:
23705
OMIM:
605686
UCSC Genome Browser:
NM_014333
RefSeq RNA:
NM_001098517
NM_014333
RefSeq Protein:
NP_001091987
NP_055148
RefSeq DNA:
NT_033899
UniProtKB:
CADM1_HUMAN (Q9BY67)
Ensembl:
ENSG00000182985
GenAtlas:
IGSF4
GeneCard:
CADM1
IGSF4
MutDB:
IGSF4
ALFRED:
LO015175T
HuGE:
IGSF4
Comparative Toxicogenomics Database:
23705
ModBase:
Q9BY67
HGNC:
5951

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