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PharmGKB contains no Clinical Variants that meet the highest level of criteria.
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The annotations do not account for individual variations among patients, and cannot be considered inclusive of all proper methods of care or exclusive of other treatments. It remains the responsibility of the health-care provider to determine the best course of treatment for a patient. Adherence to any guideline is voluntary, with the ultimate determination regarding its application to be made solely by the clinician and the patient. PharmGKB assumes no responsibility for any injury or damage to persons or property arising out of or related to any use of the PharmGKB clinical annotations, or for any errors or omissions.
|Alternate Names:||Four-and-a-half LIM domains 1; LIM protein SLIMMER|
|Alternate Symbols:||FHL1B; FLH1A; KYO-T; MGC111107; SLIM1; XMPMA; bA535K18.1|
|PharmGKB Accession Id:||PA28141|
|Cytogenetic Location:||chrX : q26.3 - q26.3|
|GP mRNA Boundary†:||chrX : 135228861 - 135293518|
|GP Gene Boundary†:||chrX : 135218861 - 135296518|
UCSC has a Genome Browser that you can use to view PharmGKB annotations for this gene in context with many other sources of information.View on UCSC Browser
Publications related to FHL1: 3
The following icons indicate that data of a certain type is available:
- DG Dosing Guideline information is available
- DL Drug Label information is available
- CA High-level Clinical Annotation is available
- VA Variant Annotation is available
- VIP VIP information is available
- PW Pathway is available
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||An X-linked myopathy with postural muscle atrophy and generalized hypertrophy, termed XMPMA, is caused by mutations in FHL1. American journal of human genetics. 2008. Windpassinger Christian, et al.|
||X-linked dominant scapuloperoneal myopathy is due to a mutation in the gene encoding four-and-a-half-LIM protein 1. American journal of human genetics. 2008. Quinzii Catarina M, et al.|
||Classification, subtype discovery, and prediction of outcome in pediatric acute lymphoblastic leukemia by gene expression profiling. Cancer cell. 2002. Yeoh Eng-Juh, et al.|
- NCBI Gene:
- UCSC Genome Browser:
- RefSeq RNA:
- RefSeq Protein:
- RefSeq DNA: