Gene:
COL4A3
collagen, type IV, alpha 3 (Goodpasture antigen)

PharmGKB contains no dosing guidelines for this . To report known genotype-based dosing guidelines, or if you are interested in developing guidelines, click here.

PharmGKB has no annotated drug labels with pharmacogenomic information for this . If you know of a drug label with PGx, send us a message.

PharmGKB contains no Clinical Variants that meet the highest level of criteria.

Disclaimer: The PharmGKB's clinical annotations reflect expert consensus based on clinical evidence and peer-reviewed literature available at the time they are written and are intended only to assist clinicians in decision-making and to identify questions for further research. New evidence may have emerged since the time an annotation was submitted to the PharmGKB. The annotations are limited in scope and are not applicable to interventions or diseases that are not specifically identified.

The annotations do not account for individual variations among patients, and cannot be considered inclusive of all proper methods of care or exclusive of other treatments. It remains the responsibility of the health-care provider to determine the best course of treatment for a patient. Adherence to any guideline is voluntary, with the ultimate determination regarding its application to be made solely by the clinician and the patient. PharmGKB assumes no responsibility for any injury or damage to persons or property arising out of or related to any use of the PharmGKB clinical annotations, or for any errors or omissions.

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Overview

Alternate Names:  tumstatin
Alternate Symbols:  None
PharmGKB Accession Id: PA26719

Details

Cytogenetic Location: chr2 : q36.3 - q36.3
GP mRNA Boundary: chr2 : 228029281 - 228179508
GP Gene Boundary: chr2 : 228019281 - 228182508
Strand: plus

Visualization

UCSC has a Genome Browser that you can use to view PharmGKB annotations for this gene in context with many other sources of information.

View on UCSC Browser
The mRNA boundaries are calculated using the gene's default feature set from NCBI, mapped onto the UCSC Golden Path. PharmGKB sets gene boundaries by expanding the mRNA boundaries by no less than 10,000 bases upstream (5') and 3,000 bases downstream (3') to allow for potential regulatory regions.
No related genes are available

Curated Information ?

Publications related to COL4A3: 1

No Dosing Guideline available No Drug Label available No Clinical Annotation available No Variant Annotation available No VIP available No VIP available
Mutations in KCNJ13 cause autosomal-dominant snowflake vitreoretinal degeneration. American journal of human genetics. 2008. Hejtmancik J Fielding, et al. PubMed

LinkOuts

NCBI Gene:
1285
OMIM:
120070
141200
203780
UCSC Genome Browser:
NM_000091
RefSeq RNA:
NM_000091
NM_031362
NM_031365
NM_031366
RefSeq Protein:
NP_000082
NP_112730
NP_112733
NP_112734
RefSeq DNA:
NG_011591
NT_005403
UniProtKB:
CO4A3_HUMAN (Q01955)
Ensembl:
ENSG00000169031
GenAtlas:
COL4A3
GeneCard:
COL4A3
MutDB:
COL4A3
ALFRED:
LO010671P
HuGE:
COL4A3
Comparative Toxicogenomics Database:
1285
ModBase:
Q01955
HumanCyc Gene:
HS09868
HGNC:
2204

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