Gene:
CGA
glycoprotein hormones, alpha polypeptide

PharmGKB contains no dosing guidelines for this . To report known genotype-based dosing guidelines, or if you are interested in developing guidelines, click here.

PharmGKB has no annotated drug labels with pharmacogenomic information for this . If you know of a drug label with PGx, send us a message.

PharmGKB contains no Clinical Variants that meet the highest level of criteria.

Disclaimer: The PharmGKB's clinical annotations reflect expert consensus based on clinical evidence and peer-reviewed literature available at the time they are written and are intended only to assist clinicians in decision-making and to identify questions for further research. New evidence may have emerged since the time an annotation was submitted to the PharmGKB. The annotations are limited in scope and are not applicable to interventions or diseases that are not specifically identified.

The annotations do not account for individual variations among patients, and cannot be considered inclusive of all proper methods of care or exclusive of other treatments. It remains the responsibility of the health-care provider to determine the best course of treatment for a patient. Adherence to any guideline is voluntary, with the ultimate determination regarding its application to be made solely by the clinician and the patient. PharmGKB assumes no responsibility for any injury or damage to persons or property arising out of or related to any use of the PharmGKB clinical annotations, or for any errors or omissions.

? = Mouse-over for quick help

Overview

Alternate Names:  chorionic gonadotropin, alpha polypeptide; follicle-stimulating hormone alpha subunit; glycoprotein hormones alpha chain; luteinizing hormone alpha chain; lutropin alpha chain; thyroid-stimulating hormone alpha chain
Alternate Symbols:  FSHA; GPHA1; GPHa; HCG; LHA; TSHA
PharmGKB Accession Id: PA26433

Details

Cytogenetic Location: chr6 : q12 - q21
GP mRNA Boundary: chr6 : 87795216 - 87804865
GP Gene Boundary: chr6 : 87792216 - 87814865
Strand: minus

Visualization

UCSC has a Genome Browser that you can use to view PharmGKB annotations for this gene in context with many other sources of information.

View on UCSC Browser
The mRNA boundaries are calculated using the gene's default feature set from NCBI, mapped onto the UCSC Golden Path. PharmGKB sets gene boundaries by expanding the mRNA boundaries by no less than 10,000 bases upstream (5') and 3,000 bases downstream (3') to allow for potential regulatory regions.
No related genes are available

Curated Information ?

Evidence Drug
No Dosing Guideline available No Drug Label available No Clinical Annotation available No Variant Annotation available No VIP available No VIP available
levothyroxine
No related diseases are available

Publications related to CGA: 1

No Dosing Guideline available No Drug Label available No Clinical Annotation available No Variant Annotation available No VIP available No VIP available
Drugs and thyroid function. The New England journal of medicine. 1995. Surks M I, et al. PubMed

LinkOuts

NCBI Gene:
1081
OMIM:
118850
UCSC Genome Browser:
NM_000735
RefSeq RNA:
NM_000735
RefSeq Protein:
NP_000726
RefSeq DNA:
NT_007299
UniProtKB:
GLHA_HUMAN (P01215)
Q6I9S8_HUMAN (Q6I9S8)
Ensembl:
ENSG00000135346
GenAtlas:
CGA
GeneCard:
CGA
MutDB:
CGA
ALFRED:
LO172711T
HuGE:
CGA
Comparative Toxicogenomics Database:
1081
HumanCyc Gene:
HS05985
HGNC:
1885

Common Searches