Gene:
CD97
CD97 molecule

PharmGKB contains no dosing guidelines for this . To report known genotype-based dosing guidelines, or if you are interested in developing guidelines, click here.

PharmGKB has no annotated drug labels with pharmacogenomic information for this . If you know of a drug label with PGx, send us a message.

PharmGKB contains no Clinical Variants that meet the highest level of criteria.

Disclaimer: The PharmGKB's clinical annotations reflect expert consensus based on clinical evidence and peer-reviewed literature available at the time they are written and are intended only to assist clinicians in decision-making and to identify questions for further research. New evidence may have emerged since the time an annotation was submitted to the PharmGKB. The annotations are limited in scope and are not applicable to interventions or diseases that are not specifically identified.

The annotations do not account for individual variations among patients, and cannot be considered inclusive of all proper methods of care or exclusive of other treatments. It remains the responsibility of the health-care provider to determine the best course of treatment for a patient. Adherence to any guideline is voluntary, with the ultimate determination regarding its application to be made solely by the clinician and the patient. PharmGKB assumes no responsibility for any injury or damage to persons or property arising out of or related to any use of the PharmGKB clinical annotations, or for any errors or omissions.

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Overview

Alternate Names:  leukocyte antigen CD97; seven transmembrane helix receptor; seven-span transmembrane protein; seven-transmembrane, heterodimeric receptor associated with inflammation
Alternate Symbols:  TM7LN1
PharmGKB Accession Id: PA26248

Details

Cytogenetic Location: chr19 : p13.12 - p13.12
GP mRNA Boundary: chr19 : 14491403 - 14519537
GP Gene Boundary: chr19 : 14481403 - 14522537
Strand: plus

Visualization

UCSC has a Genome Browser that you can use to view PharmGKB annotations for this gene in context with many other sources of information.

View on UCSC Browser
The mRNA boundaries are calculated using the gene's default feature set from NCBI, mapped onto the UCSC Golden Path. PharmGKB sets gene boundaries by expanding the mRNA boundaries by no less than 10,000 bases upstream (5') and 3,000 bases downstream (3') to allow for potential regulatory regions.
No related genes are available

Curated Information ?

Curated Information ?

Publications related to CD97: 1

No Dosing Guideline available No Drug Label available No Clinical Annotation available No Variant Annotation available No VIP available No VIP available
Promoter Polymorphisms in the beta-2 Adrenergic Receptor Are Associated With Drug-Induced Gene Expression Changes and Response in Acute Lymphoblastic Leukemia. Clinical pharmacology and therapeutics. 2010. Pottier N, et al. PubMed

LinkOuts

NCBI Gene:
976
OMIM:
601211
UCSC Genome Browser:
NM_001784
RefSeq RNA:
NM_001025160
NM_001784
NM_078481
RefSeq Protein:
NP_001020331
NP_001775
NP_510966
RefSeq DNA:
NT_011295
UniProtKB:
CD97_HUMAN (P48960)
Ensembl:
ENSG00000123146
GenAtlas:
CD97
GeneCard:
CD97
MutDB:
CD97
ALFRED:
LO090965D
HuGE:
CD97
Comparative Toxicogenomics Database:
976
ModBase:
P48960
HumanCyc Gene:
HS04635
IUPHAR Receptor:
CD97 (177)
HGNC:
1711

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