Gene:
CCR3
chemokine (C-C motif) receptor 3

PharmGKB contains no dosing guidelines for this . To report known genotype-based dosing guidelines, or if you are interested in developing guidelines, click here.

PharmGKB has no annotated drug labels with pharmacogenomic information for this . If you know of a drug label with PGx, send us a message.

PharmGKB contains no Clinical Variants that meet the highest level of criteria.

Disclaimer: The PharmGKB's clinical annotations reflect expert consensus based on clinical evidence and peer-reviewed literature available at the time they are written and are intended only to assist clinicians in decision-making and to identify questions for further research. New evidence may have emerged since the time an annotation was submitted to the PharmGKB. The annotations are limited in scope and are not applicable to interventions or diseases that are not specifically identified.

The annotations do not account for individual variations among patients, and cannot be considered inclusive of all proper methods of care or exclusive of other treatments. It remains the responsibility of the health-care provider to determine the best course of treatment for a patient. Adherence to any guideline is voluntary, with the ultimate determination regarding its application to be made solely by the clinician and the patient. PharmGKB assumes no responsibility for any injury or damage to persons or property arising out of or related to any use of the PharmGKB clinical annotations, or for any errors or omissions.

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Overview

Alternate Names:  CMKBR3
Alternate Symbols:  CC-CKR-3; CD193; CKR3
PharmGKB Accession Id: PA26168

Details

Cytogenetic Location: chr3 : p21.31 - p21.31
GP mRNA Boundary: chr3 : 46283872 - 46308197
GP Gene Boundary: chr3 : 46273872 - 46311197
Strand: plus

Visualization

UCSC has a Genome Browser that you can use to view PharmGKB annotations for this gene in context with many other sources of information.

View on UCSC Browser
The mRNA boundaries are calculated using the gene's default feature set from NCBI, mapped onto the UCSC Golden Path. PharmGKB sets gene boundaries by expanding the mRNA boundaries by no less than 10,000 bases upstream (5') and 3,000 bases downstream (3') to allow for potential regulatory regions.

LinkOuts

NCBI Gene:
1232
OMIM:
601268
UCSC Genome Browser:
NM_001837
RefSeq RNA:
NM_001164680
NM_001837
NM_178328
NM_178329
RefSeq Protein:
NP_001158152
NP_001828
NP_847898
NP_847899
RefSeq DNA:
NT_022517
HuGE:
CCR3
Comparative Toxicogenomics Database:
1232
ModBase:
P51677
IUPHAR Receptor:
CCR3 (60)
HGNC:
1604

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