Gene:
CAPNS1
calpain, small subunit 1

PharmGKB contains no prescribing info for this . Contact us to report known genotype-based dosing guidelines, or if you are interested in developing guidelines.

PharmGKB has no annotated drug labels with pharmacogenomic information for this . If you know of a drug label with PGx, send us a message.

PharmGKB contains no Clinical Variants that meet the highest level of criteria.

Disclaimer: The PharmGKB's clinical annotations reflect expert consensus based on clinical evidence and peer-reviewed literature available at the time they are written and are intended only to assist clinicians in decision-making and to identify questions for further research. New evidence may have emerged since the time an annotation was submitted to the PharmGKB. The annotations are limited in scope and are not applicable to interventions or diseases that are not specifically identified.

The annotations do not account for individual variations among patients, and cannot be considered inclusive of all proper methods of care or exclusive of other treatments. It remains the responsibility of the health-care provider to determine the best course of treatment for a patient. Adherence to any guideline is voluntary, with the ultimate determination regarding its application to be made solely by the clinician and the patient. PharmGKB assumes no responsibility for any injury or damage to persons or property arising out of or related to any use of the PharmGKB clinical annotations, or for any errors or omissions.

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Overview

Alternate Names:  CAPN4
Alternate Symbols:  30K; CANP; CANPS; CDPS
PharmGKB Accession Id: PA26067

Details

Cytogenetic Location: chr19 : q13.12 - q13.12
GP mRNA Boundary: chr19 : 36630918 - 36641255
GP Gene Boundary: chr19 : 36620918 - 36644255
Strand: plus

Visualization

UCSC has a Genome Browser that you can use to view PharmGKB annotations for this gene in context with many other sources of information.

View on UCSC Browser
The mRNA boundaries are calculated using the gene's default feature set from NCBI, mapped onto the UCSC Golden Path. PharmGKB sets gene boundaries by expanding the mRNA boundaries by no less than 10,000 bases upstream (5') and 3,000 bases downstream (3') to allow for potential regulatory regions.

LinkOuts

NCBI Gene:
826
OMIM:
114170
UCSC Genome Browser:
NM_001749
RefSeq RNA:
NM_001003962
NM_001749
RefSeq Protein:
NP_001003962
NP_001740
RefSeq DNA:
NT_011109
UniProtKB:
CPNS1_HUMAN (P04632)
Ensembl:
ENSG00000126247
GenAtlas:
CAPNS1
GeneCard:
CAPNS1
MutDB:
CAPNS1
ALFRED:
LO027509X
HuGE:
CAPNS1
Comparative Toxicogenomics Database:
826
ModBase:
P04632
HumanCyc Gene:
HS05003
HGNC:
1481

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