Gene:
ANP32A
acidic (leucine-rich) nuclear phosphoprotein 32 family, member A

PharmGKB contains no dosing guidelines for this . To report known genotype-based dosing guidelines, or if you are interested in developing guidelines, click here.

PharmGKB has no annotated drug labels with pharmacogenomic information for this . If you know of a drug label with PGx, send us a message.

PharmGKB contains no Clinical Variants that meet the highest level of criteria.

Disclaimer: The PharmGKB's clinical annotations reflect expert consensus based on clinical evidence and peer-reviewed literature available at the time they are written and are intended only to assist clinicians in decision-making and to identify questions for further research. New evidence may have emerged since the time an annotation was submitted to the PharmGKB. The annotations are limited in scope and are not applicable to interventions or diseases that are not specifically identified.

The annotations do not account for individual variations among patients, and cannot be considered inclusive of all proper methods of care or exclusive of other treatments. It remains the responsibility of the health-care provider to determine the best course of treatment for a patient. Adherence to any guideline is voluntary, with the ultimate determination regarding its application to be made solely by the clinician and the patient. PharmGKB assumes no responsibility for any injury or damage to persons or property arising out of or related to any use of the PharmGKB clinical annotations, or for any errors or omissions.

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Overview

Alternate Names:  C15orf1
Alternate Symbols:  I1PP2A; LANP; MAPM; PHAPI; PP32; mapmodulin
PharmGKB Accession Id: PA24811

Details

Cytogenetic Location: chr15 : q23 - q23
GP mRNA Boundary: chr15 : 69070874 - 69113261
GP Gene Boundary: chr15 : 69067874 - 69123261
Strand: minus

Visualization

UCSC has a Genome Browser that you can use to view PharmGKB annotations for this gene in context with many other sources of information.

View on UCSC Browser
The mRNA boundaries are calculated using the gene's default feature set from NCBI, mapped onto the UCSC Golden Path. PharmGKB sets gene boundaries by expanding the mRNA boundaries by no less than 10,000 bases upstream (5') and 3,000 bases downstream (3') to allow for potential regulatory regions.

PharmGKB Curated Pathways

Pathways created internally by PharmGKB based primarily on literature evidence.

PharmGKB contains no curated pathways for this gene. If you would like to volunteer to work on a pathway, please let us know.

External Pathways

Links to non-PharmGKB pathways.

  1. granzyme a mediated apoptosis pathway - (BioCarta via Pathway Interaction Database)

LinkOuts

NCBI Gene:
8125
OMIM:
600832
UCSC Genome Browser:
NM_006305
RefSeq RNA:
NM_006305
RefSeq Protein:
NP_006296
RefSeq DNA:
NT_010194
UniProtKB:
AN32A_HUMAN (P39687)
Ensembl:
ENSG00000140350
GenAtlas:
ANP32A
GeneCard:
ANP32A
MutDB:
ANP32A
ALFRED:
LO053785C
HuGE:
ANP32A
Comparative Toxicogenomics Database:
8125
ModBase:
P39687
HumanCyc Gene:
HS06704
HGNC:
13233

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