Gene:
ALDH7A1
aldehyde dehydrogenase 7 family, member A1

PharmGKB contains no dosing guidelines for this . To report known genotype-based dosing guidelines, or if you are interested in developing guidelines, click here.

PharmGKB has no annotated drug labels with pharmacogenomic information for this . If you know of a drug label with PGx, send us a message.

PharmGKB contains no Clinical Variants that meet the highest level of criteria.

Disclaimer: The PharmGKB's clinical annotations reflect expert consensus based on clinical evidence and peer-reviewed literature available at the time they are written and are intended only to assist clinicians in decision-making and to identify questions for further research. New evidence may have emerged since the time an annotation was submitted to the PharmGKB. The annotations are limited in scope and are not applicable to interventions or diseases that are not specifically identified.

The annotations do not account for individual variations among patients, and cannot be considered inclusive of all proper methods of care or exclusive of other treatments. It remains the responsibility of the health-care provider to determine the best course of treatment for a patient. Adherence to any guideline is voluntary, with the ultimate determination regarding its application to be made solely by the clinician and the patient. PharmGKB assumes no responsibility for any injury or damage to persons or property arising out of or related to any use of the PharmGKB clinical annotations, or for any errors or omissions.

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Overview

Alternate Names:  26g turgor protein homolog; ATQ1; P6c dehydrogenase; alpha-AASA dehydrogenase; alpha-aminoadipic semialdehyde dehydrogenase; antiquitin 1; delta1-piperideine-6-carboxylate dehydrogenease
Alternate Symbols:  EPD; PDE
PharmGKB Accession Id: PA24704

Details

Cytogenetic Location: chr5 : q23.2 - q23.2
GP mRNA Boundary: chr5 : 125877533 - 125931082
GP Gene Boundary: chr5 : 125874533 - 125941082
Strand: minus

Visualization

UCSC has a Genome Browser that you can use to view PharmGKB annotations for this gene in context with many other sources of information.

View on UCSC Browser
The mRNA boundaries are calculated using the gene's default feature set from NCBI, mapped onto the UCSC Golden Path. PharmGKB sets gene boundaries by expanding the mRNA boundaries by no less than 10,000 bases upstream (5') and 3,000 bases downstream (3') to allow for potential regulatory regions.

Publications related to ALDH7A1: 1

No Dosing Guideline available No Drug Label available No Clinical Annotation available No Variant Annotation available No VIP available No VIP available
Identification of genetic variants contributing to cisplatin-induced cytotoxicity by use of a genomewide approach. American journal of human genetics. 2007. Huang R Stephanie, et al. PubMed

LinkOuts

UniProtKB:
AL7A1_HUMAN (P49419)
Ensembl:
ENSG00000164904
GenAtlas:
ALDH7A1
GeneCard:
ALDH7A1
MutDB:
ALDH7A1
ALFRED:
LO027035R
HuGE:
ALDH7A1
Comparative Toxicogenomics Database:
501
ModBase:
P49419
HumanCyc Gene:
HS09157
HGNC:
877

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