Gene:
LPAR3
lysophosphatidic acid receptor 3

PharmGKB contains no dosing guidelines for this . To report known genotype-based dosing guidelines, or if you are interested in developing guidelines, click here.

PharmGKB has no annotated drug labels with pharmacogenomic information for this . If you know of a drug label with PGx, send us a message.

PharmGKB contains no Clinical Variants that meet the highest level of criteria.

Disclaimer: The PharmGKB's clinical annotations reflect expert consensus based on clinical evidence and peer-reviewed literature available at the time they are written and are intended only to assist clinicians in decision-making and to identify questions for further research. New evidence may have emerged since the time an annotation was submitted to the PharmGKB. The annotations are limited in scope and are not applicable to interventions or diseases that are not specifically identified.

The annotations do not account for individual variations among patients, and cannot be considered inclusive of all proper methods of care or exclusive of other treatments. It remains the responsibility of the health-care provider to determine the best course of treatment for a patient. Adherence to any guideline is voluntary, with the ultimate determination regarding its application to be made solely by the clinician and the patient. PharmGKB assumes no responsibility for any injury or damage to persons or property arising out of or related to any use of the PharmGKB clinical annotations, or for any errors or omissions.

? = Mouse-over for quick help

Overview

Alternate Names:  EDG7
Alternate Symbols:  Edg-7; HOFNH30; LP-A3; LPA3; RP4-678I3
PharmGKB Accession Id: PA162394213

Details

Cytogenetic Location: chr1 : p22.3 - p22.3
GP mRNA Boundary: chr1 : 85279086 - 85358896
GP Gene Boundary: chr1 : 85276086 - 85368896
Strand: minus

Visualization

UCSC has a Genome Browser that you can use to view PharmGKB annotations for this gene in context with many other sources of information.

View on UCSC Browser
The mRNA boundaries are calculated using the gene's default feature set from NCBI, mapped onto the UCSC Golden Path. PharmGKB sets gene boundaries by expanding the mRNA boundaries by no less than 10,000 bases upstream (5') and 3,000 bases downstream (3') to allow for potential regulatory regions.

PharmGKB Curated Pathways

Pathways created internally by PharmGKB based primarily on literature evidence.

PharmGKB contains no curated pathways for this gene. If you would like to volunteer to work on a pathway, please let us know.

External Pathways

Links to non-PharmGKB pathways.

  1. LPA receptor mediated events - (Pathway Interaction Database NCI-Nature Curated)
  2. rho-selective guanine exchange factor akap13 mediates stress fiber formation - (BioCarta via Pathway Interaction Database)

LinkOuts

NCBI Gene:
23566
OMIM:
605106
RefSeq RNA:
NM_012152
RefSeq Protein:
NP_036284
RefSeq DNA:
NT_032977
UniProtKB:
LPAR3_HUMAN (Q9UBY5)
Ensembl:
ENSG00000171517
GeneCard:
LPAR3
ALFRED:
LO019150Q
ModBase:
Q9UBY5
HumanCyc Gene:
HS10330
IUPHAR Receptor:
LPA3 (274)
HGNC:
14298

Common Searches