DBF4 homolog (S. cerevisiae)

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PharmGKB contains no Clinical Variants that meet the highest level of criteria.

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The annotations do not account for individual variations among patients, and cannot be considered inclusive of all proper methods of care or exclusive of other treatments. It remains the responsibility of the health-care provider to determine the best course of treatment for a patient. Adherence to any guideline is voluntary, with the ultimate determination regarding its application to be made solely by the clinician and the patient. PharmGKB assumes no responsibility for any injury or damage to persons or property arising out of or related to any use of the PharmGKB clinical annotations, or for any errors or omissions.

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Alternate Names:  DBF4 homolog (S. cerevisiae); DBF4 zinc finger A; activator of S phase kinase; chiffon homolog (Drosophila); zinc finger, DBF-type containing 1
Alternate Symbols:  ASK; DBF4A; ZDBF1; chif
PharmGKB Accession Id: PA142672016


Cytogenetic Location: chr7 : q21.3 - q21.12
GP mRNA Boundary: chr7 : 87505544 - 87538856
GP Gene Boundary: chr7 : 87495544 - 87541856
Strand: plus
The mRNA boundaries are calculated using the gene's default feature set from NCBI, mapped onto the UCSC Golden Path. PharmGKB sets gene boundaries by expanding the mRNA boundaries by no less than 10,000 bases upstream (5') and 3,000 bases downstream (3') to allow for potential regulatory regions.

PharmGKB Curated Pathways

Pathways created internally by PharmGKB based primarily on literature evidence.

PharmGKB contains no curated pathways for this gene. If you would like to volunteer to work on a pathway, please let us know.

External Pathways

Links to non-PharmGKB pathways.

  1. Activation of ATR in response to replication stress - (Reactome via Pathway Interaction Database)
  2. Activation of the pre-replicative complex - (Reactome via Pathway Interaction Database)


Comparative Toxicogenomics Database:
HumanCyc Gene:

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