Gene:
ABHD5
abhydrolase domain containing 5

PharmGKB contains no dosing guidelines for this . To report known genotype-based dosing guidelines, or if you are interested in developing guidelines, click here.

PharmGKB has no annotated drug labels with pharmacogenomic information for this . If you know of a drug label with PGx, send us a message.

PharmGKB contains no Clinical Variants that meet the highest level of criteria.

Disclaimer: The PharmGKB's clinical annotations reflect expert consensus based on clinical evidence and peer-reviewed literature available at the time they are written and are intended only to assist clinicians in decision-making and to identify questions for further research. New evidence may have emerged since the time an annotation was submitted to the PharmGKB. The annotations are limited in scope and are not applicable to interventions or diseases that are not specifically identified.

The annotations do not account for individual variations among patients, and cannot be considered inclusive of all proper methods of care or exclusive of other treatments. It remains the responsibility of the health-care provider to determine the best course of treatment for a patient. Adherence to any guideline is voluntary, with the ultimate determination regarding its application to be made solely by the clinician and the patient. PharmGKB assumes no responsibility for any injury or damage to persons or property arising out of or related to any use of the PharmGKB clinical annotations, or for any errors or omissions.

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Overview

Alternate Names:  None
Alternate Symbols:  CGI-58; NCIE2
PharmGKB Accession Id: PA134891622

Details

Cytogenetic Location: chr3 : p21.33 - p21.33
GP mRNA Boundary: chr3 : 43732375 - 43764217
GP Gene Boundary: chr3 : 43722375 - 43767217
Strand: plus

Visualization

UCSC has a Genome Browser that you can use to view PharmGKB annotations for this gene in context with many other sources of information.

View on UCSC Browser
The mRNA boundaries are calculated using the gene's default feature set from NCBI, mapped onto the UCSC Golden Path. PharmGKB sets gene boundaries by expanding the mRNA boundaries by no less than 10,000 bases upstream (5') and 3,000 bases downstream (3') to allow for potential regulatory regions.
No related genes are available

Curated Information ?

Evidence Disease
No Dosing Guideline available No Drug Label available No Clinical Annotation available No Variant Annotation available No VIP available No VIP available
Obesity

Publications related to ABHD5: 1

No Dosing Guideline available No Drug Label available No Clinical Annotation available No Variant Annotation available No VIP available No VIP available
Adipocyte triglyceride lipase expression in human obesity. American journal of physiology. Endocrinology and metabolism. 2007. Steinberg Gregory R, et al. PubMed

LinkOuts

NCBI Gene:
51099
OMIM:
275630
604780
RefSeq RNA:
NM_016006
RefSeq Protein:
NP_057090
RefSeq DNA:
NG_007090
NT_022517
UniProtKB:
ABHD5_HUMAN (Q8WTS1)
Ensembl:
ENSG00000011198
GeneCard:
ABHD5
ALFRED:
LO178647H
HuGE:
ABHD5
Comparative Toxicogenomics Database:
51099
ModBase:
Q8WTS1
HumanCyc Gene:
HS00306
HGNC:
21396

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