Drug/Small Molecule:

oxytocin

Synthetic 9 residue cyclic peptide. The hormone is prepared synthetically to avoid possible contamination with vasopressin (ADH) and other small polypeptides with biologic activity. (source: Drug Bank)

To assist in labor, elective labor induction, uterine contraction induction (source: Drug Bank)

Binds the oxytocin receptor which leads to an increase in intracellular calcium levels. (source: Drug Bank)

Used to induce labor or to enhance uterine contractions during labor. Uterine motility depends on the formation of the contractile protein actomyosin under the influence of the Ca2+-dependent phosphorylating enzyme myosin light-chain kinase. Oxytocin promotes contractions by increasing the intracellular Ca2+, which in turn activates myosins light chain kinase.. Oxytocin has specific receptors in the muscle llining of the uterus and the receptor concentration increases greatly during pregnancy, reaching a maximum in early labor at term. (source: Drug Bank)

30% (source: Drug Bank)

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