VIP Annotations

The Very Important Pharmacogenes, or VIP project, is an initiative to provide annotated information about Genes, Variants, Haplotypes and Splice Variants of particular relevance for Pharmacogenetics and Pharmacogenomics (PGx).

VIP Gene Gene Name
ABCB1 ATP-binding cassette, sub-family B (MDR/TAP), member 1
ACE angiotensin I converting enzyme
ADH1A alcohol dehydrogenase 1A (class I), alpha polypeptide
ADH1B alcohol dehydrogenase IB (class I), beta polypeptide
ADH1C alcohol dehydrogenase 1C (class I), gamma polypeptide
ADRB1 adrenergic, beta-1-, receptor
ADRB2 adrenergic, beta-2-, receptor, surface
AHR aryl hydrocarbon receptor
ALDH1A1 aldehyde dehydrogenase 1 family, member A1
ALOX5 arachidonate 5-lipoxygenase
BRCA1 breast cancer 1, early onset
COMT catechol-O-methyltransferase
CYP2A6 cytochrome P450, family 2, subfamily A, polypeptide 6
CYP2B6 cytochrome P450, family 2, subfamily B, polypeptide 6
CYP2C9 cytochrome P450, family 2, subfamily C, polypeptide 9
CYP2C19 cytochrome P450, family 2, subfamily C, polypeptide 19
CYP2D6 cytochrome P450, family 2, subfamily D, polypeptide 6
CYP2J2 cytochrome P450, family 2, subfamily J, polypeptide 2
CYP3A4 cytochrome P450, family 3, subfamily A, polypeptide 4
CYP3A5 cytochrome P450, family 3, subfamily A, polypeptide 5
DPYD dihydropyrimidine dehydrogenase
DRD2 dopamine receptor D2
F5 coagulation factor V
GSTP1 glutathione S-transferase pi
HMGCR 3-hydroxy-3-methylglutaryl-Coenzyme A reductase
KCNH2 potassium voltage-gated channel, subfamily H (eag-related), member 2
KCNJ11 potassium inwardly-rectifying channel, subfamily J, member 11
MTHFR 5,10-methylenetetrahydrofolate reductase (NADPH)
NQO1 NAD(P)H dehydrogenase, quinone 1
P2RY1 purinergic receptor P2Y, G-protein coupled, 1
P2RY12 purinergic receptor P2Y, G-protein coupled, 12
PTGIS prostaglandin I2 (prostacyclin) synthase
SCN5A sodium channel, voltage-gated, type V, alpha (long QT syndrome 3)
SLC19A1 solute carrier family 19 (folate transporter), member 1
SLCO1B1 solute carrier organic anion transporter family, member 1B1
SULT1A1 sulfotransferase family, cytosolic, 1A, phenol-preferring, member 1
TPMT thiopurine S-methyltransferase
TYMS thymidylate synthetase
UGT1A1 UDP glucuronosyltransferase 1 family, polypeptide A1
VDR vitamin D (1,25- dihydroxyvitamin D3) receptor
VKORC1 vitamin K epoxide reductase complex, subunit 1