Variant:
rs7196161 at chr16:31110981 in BCKDK, PRSS53, VKORC1

Alleles (on + chromosomal strand)
G > A
Haplotypes
This variant is used to determine: VKORC1 H1, VKORC1 H2, VKORC1 H3, VKORC1 H4, VKORC1 H5, VKORC1 H6, VKORC1 H7, VKORC1 H8, VKORC1 H9

Variant Annotations

PharmGKB variant annotations provide information about variant-drug pairs based on individual PubMed publications. Each annotation represents information from a single paper and the goal is to report the information that the author states, not an interpretation of the paper. The PMID for supporting PubMed publications is found in the "Evidence" field.

Information presented, including study size, allele frequencies and statistics is taken directly from the publication. However, if the author does not correct p-values in cases of multiple hypotheses, curators may apply a Bonferroni correction. Curators attempt to report study size based on the actual number of participants used for the calculation of the association statistics, so the number may vary slightly from what is reported in the abstract of the paper. OMB Race Category information is derived from the paper and mapped to standardized categories. Category definitions may be found by clicking on the "OMB Race Category" link.

There are 1 annotations for this variant. Register or sign in to see them.

Connected Drugs

Evidence Drug
No Dosing Guideline available No Drug Label available No Clinical Annotation available VA No VIP available No VIP available
warfarin

Publications related to rs7196161 at chr16:31110981: 1

No Dosing Guideline available No Drug Label available No Clinical Annotation available VA No VIP available No VIP available
Translational aspects of genetic factors in the prediction of drug response variability: a case study of warfarin pharmacogenomics in a multi-ethnic cohort from Asia. The pharmacogenomics journal. 2011. Chan S L, et al. [Article:21383771@PubMed]

Cross-References

UCSC Golden Path:
chr16:31110981
dbSNP:
rs7196161
Seattle SNP:
VKORC1-000381

Common Searches

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